ID VA712_ARATH Reviewed; 219 AA.
AC Q9SIQ9;
DT 17-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 147.
DE RecName: Full=Vesicle-associated membrane protein 712 {ECO:0000303|PubMed:11115874};
DE Short=AtVAMP712 {ECO:0000303|PubMed:11115874};
GN Name=VAMP712 {ECO:0000303|PubMed:11115874};
GN OrderedLocusNames=At2g25340 {ECO:0000312|Araport:AT2G25340};
GN ORFNames=T22F11.7 {ECO:0000312|EMBL:AAD23657.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11115874; DOI=10.1104/pp.124.4.1558;
RA Sanderfoot A.A., Assaad F.F., Raikhel N.V.;
RT "The Arabidopsis genome. An abundance of soluble N-ethylmaleimide-sensitive
RT factor adaptor protein receptors.";
RL Plant Physiol. 124:1558-1569(2000).
RN [4]
RP TISSUE SPECIFICITY, AND SUBCELLULAR LOCATION.
RX PubMed=15342965; DOI=10.1247/csf.29.49;
RA Uemura T., Ueda T., Ohniwa R.L., Nakano A., Takeyasu K., Sato M.H.;
RT "Systematic analysis of SNARE molecules in Arabidopsis: dissection of the
RT post-Golgi network in plant cells.";
RL Cell Struct. Funct. 29:49-65(2004).
RN [5]
RP DOMAIN.
RX PubMed=15876431; DOI=10.1016/j.febslet.2005.04.022;
RA Uemura T., Sato M.H., Takeyasu K.;
RT "The longin domain regulates subcellular targeting of VAMP7 in Arabidopsis
RT thaliana.";
RL FEBS Lett. 579:2842-2846(2005).
CC -!- FUNCTION: Involved in the targeting and/or fusion of transport vesicles
CC to their target membrane. {ECO:0000305|PubMed:11115874}.
CC -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000269|PubMed:15342965};
CC Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q12255}.
CC Prevacuolar compartment membrane {ECO:0000269|PubMed:15342965}; Single-
CC pass type IV membrane protein {ECO:0000250|UniProtKB:Q12255}.
CC -!- TISSUE SPECIFICITY: Expressed in flowers, leaves, stems and roots.
CC {ECO:0000269|PubMed:15342965}.
CC -!- DOMAIN: The longin domain is critical for the vacuolar localization.
CC {ECO:0000269|PubMed:15876431}.
CC -!- SIMILARITY: Belongs to the synaptobrevin family. {ECO:0000305}.
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DR EMBL; AC007070; AAD23657.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07690.1; -; Genomic_DNA.
DR PIR; C84647; C84647.
DR RefSeq; NP_180106.1; NM_128091.1.
DR AlphaFoldDB; Q9SIQ9; -.
DR SMR; Q9SIQ9; -.
DR STRING; 3702.Q9SIQ9; -.
DR PaxDb; 3702-AT2G25340-1; -.
DR ProteomicsDB; 243251; -.
DR EnsemblPlants; AT2G25340.1; AT2G25340.1; AT2G25340.
DR GeneID; 817072; -.
DR Gramene; AT2G25340.1; AT2G25340.1; AT2G25340.
DR KEGG; ath:AT2G25340; -.
DR Araport; AT2G25340; -.
DR TAIR; AT2G25340; VAMP712.
DR eggNOG; KOG0859; Eukaryota.
DR HOGENOM; CLU_064620_1_2_1; -.
DR InParanoid; Q9SIQ9; -.
DR OMA; TNIMERG; -.
DR OrthoDB; 664519at2759; -.
DR PhylomeDB; Q9SIQ9; -.
DR PRO; PR:Q9SIQ9; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SIQ9; baseline and differential.
DR Genevisible; Q9SIQ9; AT.
DR GO; GO:0005774; C:vacuolar membrane; TAS:TAIR.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd14824; Longin; 1.
DR CDD; cd15843; R-SNARE; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR Gene3D; 3.30.450.50; Longin domain; 1.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR010908; Longin_dom.
DR InterPro; IPR001388; Synaptobrevin-like.
DR InterPro; IPR042855; V_SNARE_CC.
DR PANTHER; PTHR21136; SNARE PROTEINS; 1.
DR PANTHER; PTHR21136:SF172; VESICLE-ASSOCIATED MEMBRANE PROTEIN 711-RELATED; 1.
DR Pfam; PF13774; Longin; 1.
DR Pfam; PF00957; Synaptobrevin; 1.
DR PRINTS; PR00219; SYNAPTOBREVN.
DR SMART; SM01270; Longin; 1.
DR SUPFAM; SSF58038; SNARE fusion complex; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS50859; LONGIN; 1.
DR PROSITE; PS00417; SYNAPTOBREVIN; 1.
DR PROSITE; PS50892; V_SNARE; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Membrane; Protein transport; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport; Vacuole.
FT CHAIN 1..219
FT /note="Vesicle-associated membrane protein 712"
FT /id="PRO_0000206751"
FT TOPO_DOM 1..189
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 190..210
FT /note="Helical; Anchor for type IV membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 211..219
FT /note="Vesicular"
FT /evidence="ECO:0000255"
FT DOMAIN 7..111
FT /note="Longin"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00231"
FT DOMAIN 126..186
FT /note="v-SNARE coiled-coil homology"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00290"
SQ SEQUENCE 219 AA; 24966 MW; 7A63C85A140913B9 CRC64;
MSILYALVAR GTVVLAELST TSTNASTIAK QILEKIPGNG DSHVSYSQDR YVFHVKRTDG
LTVLCMADED AGRRIPFSFL EDIHQRFVRT YGRAIHSAQA YAMNDEFSRV LNQQIEYYSN
DPNADTISRI KGEMNQVRDV MIENIDNILD RGERLELLVD KTANMQGNTF RFRKQTRRFN
NTVWWRNCKL TLLLILVLLV IIYIGVAFAC HGPTLPSCV
//
