ID W0A7I6_9SPHN Unreviewed; 930 AA.
AC W0A7I6;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Multidrug ABC transporter ATP-binding protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=NX02_02700 {ECO:0000313|EMBL:AHE52298.1};
OS Sphingomonas sanxanigenens DSM 19645 = NX02.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=1123269 {ECO:0000313|EMBL:AHE52298.1, ECO:0000313|Proteomes:UP000018851};
RN [1] {ECO:0000313|EMBL:AHE52298.1, ECO:0000313|Proteomes:UP000018851}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NX02 {ECO:0000313|EMBL:AHE52298.1,
RC ECO:0000313|Proteomes:UP000018851};
RA Ma T., Huang H., Wu M., Li X., Li G.;
RT "Completed genome of Sphingomonas sanxanigenens NX02.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP006644; AHE52298.1; -; Genomic_DNA.
DR RefSeq; WP_025290623.1; NZ_CP006644.1.
DR AlphaFoldDB; W0A7I6; -.
DR STRING; 1123269.NX02_02700; -.
DR KEGG; ssan:NX02_02700; -.
DR PATRIC; fig|1123269.5.peg.522; -.
DR eggNOG; COG0842; Bacteria.
DR eggNOG; COG1129; Bacteria.
DR HOGENOM; CLU_000604_16_3_5; -.
DR OrthoDB; 9805029at2; -.
DR Proteomes; UP000018851; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03230; ABC_DR_subfamily_A; 1.
DR Gene3D; 3.40.1710.10; abc type-2 transporter like domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR047651; ABC2_perm_RbbA.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR047817; ABC2_TM_bact-type.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; NF033858; ABC2_perm_RbbA; 1.
DR PANTHER; PTHR43038; ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1; 1.
DR PANTHER; PTHR43038:SF4; RIBOSOME-ASSOCIATED ATPASE; 1.
DR Pfam; PF12698; ABC2_membrane_3; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51012; ABC_TM2; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000018851};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 578..598
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 733..757
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 788..810
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 816..839
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 846..867
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 906..925
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..248
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 277..507
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 695..928
FT /note="ABC transmembrane type-2"
FT /evidence="ECO:0000259|PROSITE:PS51012"
SQ SEQUENCE 930 AA; 100896 MW; CAB091450CAFD49A CRC64;
MIPPAQILPE EAIRIESLSH RYGGIVALNE VSLSLPKGKT TALVGPDGVG KSTLLGLISG
VKKLQTGRLS VLGFDLAERR KREDFLARVA YMPQGLGRNL YPTLSVRENI DFFGRLFGLS
AAEREAHLRR LLDATGLAPF PDRPAGKLSG GMKQKLGLCC SLVHDPDLLI LDEPTTGVDP
LSRRQFWELV DAMCAERPDM TVLVSTAYME EAERFGHLVA MDDGKVIAQG DTGEIMREAG
ADTLEAAYVR LLPQDKRPSG DALVVPAWQD KGEAPAIEAH DLTRRFGDFV AVDHVNFRIG
RGEIFGFLGS NGCGKTTTMK MLTGLLDATD GTASLFGRPI APGDMETRMR VGYMSQAFSL
YEELSVRQNL VLHARLYRVP RAQAGELVSA ALAQFELEAH ADAVPSALPL GIRQRLQLAA
ACLHRPEILI LDEPTSGVDP AARDMFWRHL IRLSRDEGVT IFVSTHFMNE AERCDRISLM
HRGRVLAVGA PAELTQRYDA ERLEDAFIAV LEKDNDEVPT AAPATLPTDT SAASPTVAAG
ARAMAMGVPR LPTAAGNWPG FAWAFARREA TELMRDRIRL AFALIGPIIL LCIAAYSISF
DVQNIRLAVL DHDCSAASRD LQRYFEGSRY FRVEPELQSD AAAEQALREA SAKMVLDIPP
GFGRDLAAGR RPAIDVRIDG ASPFPASNAR AYAEAILLRY SIDQLRSTQL FAIPDLSSTI
EPRFIYNQEF RSIYAMAPGV LMLCMILIPA MLTALGVVRE KEIGSITNLY ASPASLGAFL
VGKQMPYALL AMISFVTLIL VTVFILGVPL KGSLPALLIG GFLFILSVTG LGLMISAFVR
SQVAAIFATS LICLIPSVNF SGLLYPVSTL TGPSHMIGLT FPSSWFQIVS LGTFTKGLGM
ASFGQAYLAL MALALLFVGG ARLMLGKQEK
//
