ID W0B7E7_9GAMM Unreviewed; 652 AA.
AC W0B7E7;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Rad3-related DNA helicase {ECO:0000313|EMBL:AHE66473.1};
DE EC=3.6.4.12 {ECO:0000313|EMBL:AHE66473.1};
GN ORFNames=Loa_00914 {ECO:0000313|EMBL:AHE66473.1};
OS Legionella oakridgensis ATCC 33761 = DSM 21215.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=1268635 {ECO:0000313|EMBL:AHE66473.1, ECO:0000313|Proteomes:UP000018838};
RN [1] {ECO:0000313|EMBL:AHE66473.1, ECO:0000313|Proteomes:UP000018838}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OR-10, ATCC 33761 {ECO:0000313|Proteomes:UP000018838};
RX PubMed=23932911; DOI=10.1016/j.ijmm.2013.07.003;
RA Brzuszkiewicz E., Schulz T., Rydzewski K., Daniel R., Gillmaier N.,
RA Dittmann C., Holland G., Schunder E., Lautner M., Eisenreich W., Luck C.,
RA Heuner K.;
RT "Legionella oakridgensis ATCC 33761 genome sequence and phenotypic
RT characterization reveals its replication capacity in amoebae.";
RL Int. J. Med. Microbiol. 303:514-528(2013).
CC -!- SIMILARITY: Belongs to the helicase family. DinG subfamily.
CC {ECO:0000256|ARBA:ARBA00038058}.
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DR EMBL; CP004006; AHE66473.1; -; Genomic_DNA.
DR RefSeq; WP_025385252.1; NZ_CP004006.1.
DR AlphaFoldDB; W0B7E7; -.
DR STRING; 1268635.Loa_00914; -.
DR KEGG; lok:Loa_00914; -.
DR PATRIC; fig|1268635.3.peg.912; -.
DR eggNOG; COG1199; Bacteria.
DR HOGENOM; CLU_012117_2_0_6; -.
DR Proteomes; UP000018838; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF47; FANCONI ANEMIA GROUP J PROTEIN; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:AHE66473.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AHE66473.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000018838}.
FT DOMAIN 25..297
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
SQ SEQUENCE 652 AA; 73236 MW; 6E685706CDE2CA50 CRC64;
MDEIETIATP ELVSQCERLL AARGRLFTAI PGYIARPSQI QLTEAIARTI ADETILVAEA
GTGTGKTFAY LIPSLLCGKK ILITTATKTL QDQLFHKDLP MLVRALGLAA RVQNLKGRAN
YLCRYRVDLH AQEGRFVSPQ CAHEILHIRE KLPQLTAGER SELPEIKEDS PVWPYVTSTG
DNCLGSECPN HQNCFLVKAR KRALEADVVV INHHLYFADS RLKEEGFGEL LPGVDVVIFD
EAHQLAEIAS NFYGERISTR QFRDLMDDIL REWPILDLVN QPLKALSFKL DQLVEQLLQS
VPGEEERLAW EKVAGCAEFI QSWEAFSAFA EEVLACFDTL EVEKHSGLER CKNRLEALLR
LLHAFAANKS KQIHWLERFK HTLVFHATPF DIAQPFRALL TRQKSSFIFT SATLTTASSF
DCFTRALGLE NVQTLNLPSP FDFTRQALLY LPRTLPDPKD GGYYDALLAK ALPVINACGG
RCFFLFTSHR ALKLVADKLM DRLNFPLLIQ GEEAKPILLQ RFRELGNAVL LGTATFWEGV
DVKGEALSCV IIDKLPFTSP VDPVIRGKMA YLKSQGLSAF DELSLPHAIL TLKQGVGRLI
RDVDDCGVLM IADPRLTARD YGRRIFASLP NMRKTRDEHG VLEFINTLFT RT
//
