ID W0BCP1_9GAMM Unreviewed; 659 AA.
AC W0BCP1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Ribonuclease G {ECO:0000256|ARBA:ARBA00017719};
GN ORFNames=Loa_00904 {ECO:0000313|EMBL:AHE66466.1};
OS Legionella oakridgensis ATCC 33761 = DSM 21215.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=1268635 {ECO:0000313|EMBL:AHE66466.1, ECO:0000313|Proteomes:UP000018838};
RN [1] {ECO:0000313|EMBL:AHE66466.1, ECO:0000313|Proteomes:UP000018838}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OR-10, ATCC 33761 {ECO:0000313|Proteomes:UP000018838};
RX PubMed=23932911; DOI=10.1016/j.ijmm.2013.07.003;
RA Brzuszkiewicz E., Schulz T., Rydzewski K., Daniel R., Gillmaier N.,
RA Dittmann C., Holland G., Schunder E., Lautner M., Eisenreich W., Luck C.,
RA Heuner K.;
RT "Legionella oakridgensis ATCC 33761 genome sequence and phenotypic
RT characterization reveals its replication capacity in amoebae.";
RL Int. J. Med. Microbiol. 303:514-528(2013).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the RNase E/G family. RNase G subfamily.
CC {ECO:0000256|ARBA:ARBA00005663}.
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DR EMBL; CP004006; AHE66466.1; -; Genomic_DNA.
DR AlphaFoldDB; W0BCP1; -.
DR STRING; 1268635.Loa_00904; -.
DR KEGG; lok:Loa_00904; -.
DR PATRIC; fig|1268635.3.peg.904; -.
DR eggNOG; COG1530; Bacteria.
DR HOGENOM; CLU_003468_3_2_6; -.
DR Proteomes; UP000018838; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd04453; S1_RNase_E; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.1260.20; Ribonuclease E, catalytic domain; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR InterPro; IPR004659; RNase_E/G.
DR InterPro; IPR048583; RNase_E_G_thioredoxin-like.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00757; RNaseEG; 1.
DR PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR PANTHER; PTHR30001:SF1; RIBONUCLEASE E_G-LIKE PROTEIN, CHLOROPLASTIC; 1.
DR Pfam; PF10150; RNase_E_G; 1.
DR Pfam; PF20833; RNase_E_G_Thio; 1.
DR Pfam; PF00575; S1; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50126; S1; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018838};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 43..125
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 563..659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 577..631
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..659
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 659 AA; 74381 MW; E3F49A7B1B2C6A84 CRC64;
MGLKMEKMLI NATQSEEVRV ALVRDNLLFD LDIECPTETK KKGNIYKATV TRREPSLDAV
FVEYGAKRQG FLPLKEIAPE YLSKHPDEFG AEKPSITTLI REGQELLVQV DKEERGNKGA
ALTTFITLAG CYLVLMPNSP RSGGISRRIE GDDRNELKET LGSLQMDEDM GLIIRTAGVG
KSQEELQADL DMLRNQWQAI KNAYNTQLSP CLIHQEGDVI IRSIRDNLRK SISEIIIDDQ
VSFVKAKQYI EQVKPDFLPN LKLYKSTIPL FNFYQVESQI ETAYQREVLL PSGGALVIDR
TEALVSIDIN SAKATSGSDI EATALNTNLE AADEIARQLR LRDLGGLVVI DFIDMNSSKN
QRDVENRLKE ALKADRARIQ VGRISRFGLL EMSRQRLRLS LGESAQEVCP RCEGRGTVRN
IQSHSLSIVR LIEEEALKEK TAEVQVQLPP DMATFIMNEK RDFIINIEKR HDVQVLIIAN
PYLQSPHYSI TRRKEDNVGK NRKPSYSLIQ QPEVEIAKTE KQATELDQPV VKPYEGKHQA
LVKESGLLQR LWNYLFANTA ELDKSKPEKK EPTKTQKAHS SQQSTSKRTQ QSGQSGYKRR
SGSHYQNRSS GGNRKRSSSG QQQSHANQPG GRVIPLNTEL SKKKHPTIIK NQTKPERCP
//
