ID W0DP24_9GAMM Unreviewed; 395 AA.
AC W0DP24;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Phosphohydrolase {ECO:0000313|EMBL:AHF00355.1};
GN ORFNames=THIAE_00090 {ECO:0000313|EMBL:AHF00355.1};
OS Thiomicrospira aerophila AL3.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Thiomicrospira.
OX NCBI_TaxID=717772 {ECO:0000313|EMBL:AHF00355.1, ECO:0000313|Proteomes:UP000005380};
RN [1] {ECO:0000313|EMBL:AHF00355.1, ECO:0000313|Proteomes:UP000005380}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AL2 {ECO:0000313|Proteomes:UP000005380};
RG DOE Joint Genome Institute;
RA Kappler U., Huntemann M., Han J., Chen A., Kyrpides N., Mavromatis K.,
RA Markowitz V., Palaniappan K., Ivanova N., Schaumberg A., Pati A.,
RA Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP007030; AHF00355.1; -; Genomic_DNA.
DR AlphaFoldDB; W0DP24; -.
DR STRING; 717772.THIAE_00090; -.
DR KEGG; tao:THIAE_00090; -.
DR eggNOG; COG3437; Bacteria.
DR HOGENOM; CLU_056947_0_0_6; -.
DR InParanoid; W0DP24; -.
DR OrthoDB; 9802066at2; -.
DR Proteomes; UP000005380; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:UniProt.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR PANTHER; PTHR45228:SF9; 3'3'-CGAMP-SPECIFIC PHOSPHODIESTERASE 2; 1.
DR PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR Pfam; PF13487; HD_5; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51832; HD_GYP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:AHF00355.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 199..395
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
FT COILED 178..205
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 395 AA; 46165 MW; 2FD6CAC49F4859C6 CRC64;
MPFSEKFQKT AVINFRILML VNLIFLVLAL FANFWLERWA LLIIHAITGL AFLMLYGMSN
LRPNYQGYPR IYLAIMAAYF YSFFWYGHID TYDLIWLLLF PPLVAFLIEK DRELILWQGG
FILGVFIFFI AAMQDVWGLV YPPMLIGAVL FSNSFISVLS WFNHRYKARF YAAQEAFQNV
LEQRVEQATQ TIRKLNDELE VSQRDVVMRL GEICEVRSKE TGQHVQRVSE YSRRLAELIN
LPEDEVQLIQ DASPLHDVGK VAIPDNILNK PGRYDEREYS IMKEHANIGY KLLNSSPQPL
LQAAAIIARD HHEWWNGKGY PNHKAQENIH IYGRIVAIAD VFDALSFERI YKPAWSDDKI
LALFNEQCGV QFDPRLCQLF LDHYDEFIAL RKKFC
//
