ID W0DYM6_MARPU Unreviewed; 928 AA.
AC W0DYM6;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00022419, ECO:0000256|HAMAP-Rule:MF_00595};
DE Short=PEPC {ECO:0000256|HAMAP-Rule:MF_00595};
DE Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_00595};
DE EC=4.1.1.31 {ECO:0000256|ARBA:ARBA00012305, ECO:0000256|HAMAP-Rule:MF_00595};
GN Name=ppc {ECO:0000256|HAMAP-Rule:MF_00595};
GN ORFNames=MARPU_07305 {ECO:0000313|EMBL:AHF03690.1};
OS Marichromatium purpuratum 984.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Marichromatium.
OX NCBI_TaxID=765910 {ECO:0000313|EMBL:AHF03690.1, ECO:0000313|Proteomes:UP000005275};
RN [1] {ECO:0000313|EMBL:AHF03690.1, ECO:0000313|Proteomes:UP000005275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=984 {ECO:0000313|EMBL:AHF03690.1,
RC ECO:0000313|Proteomes:UP000005275};
RG DOE Joint Genome Institute;
RA Bryant D.A., Huntemann M., Han J., Chen A., Kyrpides N., Mavromatis K.,
RA Markowitz V., Palaniappan K., Ivanova N., Schaumberg A., Pati A.,
RA Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC for the tricarboxylic acid cycle. {ECO:0000256|ARBA:ARBA00003670,
CC ECO:0000256|HAMAP-Rule:MF_00595}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC Evidence={ECO:0000256|ARBA:ARBA00001071, ECO:0000256|HAMAP-
CC Rule:MF_00595};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946,
CC ECO:0000256|HAMAP-Rule:MF_00595};
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00595}.
CC -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC {ECO:0000256|ARBA:ARBA00008346, ECO:0000256|HAMAP-Rule:MF_00595}.
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DR EMBL; CP007031; AHF03690.1; -; Genomic_DNA.
DR RefSeq; WP_005223784.1; NZ_CP007031.1.
DR AlphaFoldDB; W0DYM6; -.
DR STRING; 765910.MARPU_07305; -.
DR KEGG; mpur:MARPU_07305; -.
DR eggNOG; COG2352; Bacteria.
DR HOGENOM; CLU_006557_2_0_6; -.
DR OrthoDB; 9768133at2; -.
DR Proteomes; UP000005275; Chromosome.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 1.
DR HAMAP; MF_00595; PEPcase_type1; 1.
DR InterPro; IPR021135; PEP_COase.
DR InterPro; IPR022805; PEP_COase_bac/pln-type.
DR InterPro; IPR018129; PEP_COase_Lys_AS.
DR InterPro; IPR033129; PEPCASE_His_AS.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR PANTHER; PTHR30523:SF46; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR Pfam; PF00311; PEPcase; 1.
DR PRINTS; PR00150; PEPCARBXLASE.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR PROSITE; PS00781; PEPCASE_1; 1.
DR PROSITE; PS00393; PEPCASE_2; 1.
PE 3: Inferred from homology;
KW Carbon dioxide fixation {ECO:0000256|ARBA:ARBA00023300, ECO:0000256|HAMAP-
KW Rule:MF_00595};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_00595};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842, ECO:0000256|HAMAP-Rule:MF_00595};
KW Pyruvate {ECO:0000313|EMBL:AHF03690.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005275}.
FT ACT_SITE 145
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00595,
FT ECO:0000256|PROSITE-ProRule:PRU10111"
FT ACT_SITE 587
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00595,
FT ECO:0000256|PROSITE-ProRule:PRU10112"
SQ SEQUENCE 928 AA; 104499 MW; 6C00CE204C706E12 CRC64;
MNETVDDPVL EHDIELFTRL LGDVLREHSR KRVLVVVERL REGFMQLREG EDETLRARLR
ARIEGLDPQT LAEVIRAFAI YFGLVNTAEE LNAHLQRMAR VSSGERLWRG SFDDTVRRLA
ADGVAPAPFQ SLLEHLVYLP VFTAHPTEAR RRTIAEIFRR IFLAGQDLHR HRLNDEERED
KLAEIRAQIQ ILWKTDEVRV HKPQVTDEVR QGLYFFRESL FGAVPEVYRI LEKAVRRVHG
AATAAAVPSL MRFGSWIGGD RDGNPFVCPE TTELAVRMHA ELALEHYLER VGRLQRMLSH
SSALCEPAPA FLDSLDADED YWVETMGQSL RRFLNEPYRR KLAMVAHRLE ANLARVRARL
AEAETLPAAG YCDARAFLVD LRLIRDSLIH HGDASAAAGP LHDLIRLVET FGFHLVQLDL
RQESSRHTEA VAELFARQPG APYYLAFDES QRLLALVEAI VHPQPFVIDK ATLGAATRET
LETFETIARA RAEVGEQAIG QYVISMTHEA SHVLEVMLLA RLAGLAGRDR QGWFCTLQIA
PLFETIDDLA RIDAVMGRLF TDPTYRALLR ASGDQQEVML GYSDSCKDGG ILASGWRLYE
AQRKVIALAD EHGVACRLFH GRGGTVGRGG GPTHEAILAQ PADTVHGQIK FTEQGEVLSY
RYANPETARY ELTMGISGLI KASRCLIESA APERAEDLEV MAELAAHGEA AYRALVGTEG
LLDYFYACTP VDGIALLNIG SRPAHRSRGD RSLSSIRAIP WVFGWGQARL TLPGWFGIGT
ALARYRGDDP ERLVRLRRMY GEWPFFRVLL SNTQMSLFKA EMAIAREYLR LADDPPRAAA
LLAHIEAEYR LTLSEVLAVT ETDRLLADQP ALRRSLLRRN RYLDPLNHIQ VVLLERYRGE
PEAEQREQWL DPLLRSINAI AAGMRNTG
//
