ID W0EF64_9FIRM Unreviewed; 337 AA.
AC W0EF64;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=DESME_14800 {ECO:0000313|EMBL:AHF08153.1};
OS Desulfitobacterium metallireducens DSM 15288.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfitobacterium.
OX NCBI_TaxID=871968 {ECO:0000313|EMBL:AHF08153.1, ECO:0000313|Proteomes:UP000010847};
RN [1] {ECO:0000313|EMBL:AHF08153.1, ECO:0000313|Proteomes:UP000010847}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15288 {ECO:0000313|Proteomes:UP000010847};
RG DOE Joint Genome Institute;
RA Smidt H., Huntemann M., Han J., Chen A., Kyrpides N., Mavromatis K.,
RA Markowitz V., Palaniappan K., Ivanova N., Schaumberg A., Pati A.,
RA Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP007032; AHF08153.1; -; Genomic_DNA.
DR RefSeq; WP_006718538.1; NZ_CP007032.1.
DR AlphaFoldDB; W0EF64; -.
DR STRING; 871968.DESME_14800; -.
DR KEGG; dmt:DESME_14800; -.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG3706; Bacteria.
DR HOGENOM; CLU_000445_11_4_9; -.
DR OrthoDB; 9798833at2; -.
DR Proteomes; UP000010847; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08447; PAS_3; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010847};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..110
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 114..166
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 205..337
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 337 AA; 38911 MW; F15C42A260ADB906 CRC64;
MNLWDAFLDG VLILTIILVI AYIFILKRRY NQILKDAQDE AVITEIAFDK TALGMCIARP
DLSYIDINPS YCNLVGYSKD ELMNMIHKDF IYPEDRENDT PYIRDLFLGR YDTFQSIKRY
IHKQGHIVWA KATVTLVRDE GQNPKFFVTQ IQDITQTKRA EEALKKAKIE AETLASIDYL
TGCLNRRAFM IRLEEELARA MRNQSNLSMI LVDIDDFKSI NDFYGHLAGD YVLRQFSKCL
NRGIRTYDFI GRFGGEEFMI CLPDTEIQDA YQIAERMRQS VEELVMVYED SQIKITGSFG
VATSHPGIEE PIDKLIGMAD KAMYEAKSIK NRVYKSA
//
