ID W0F0L2_9BACT Unreviewed; 975 AA.
AC W0F0L2;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=NIASO_17980 {ECO:0000313|EMBL:AHF16547.1};
OS Niabella soli DSM 19437.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Niabella.
OX NCBI_TaxID=929713 {ECO:0000313|EMBL:AHF16547.1, ECO:0000313|Proteomes:UP000003586};
RN [1] {ECO:0000313|EMBL:AHF16547.1, ECO:0000313|Proteomes:UP000003586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19437 {ECO:0000313|Proteomes:UP000003586};
RG DOE Joint Genome Institute;
RA Eisen J., Huntemann M., Han J., Chen A., Kyrpides N., Mavromatis K.,
RA Markowitz V., Palaniappan K., Ivanova N., Schaumberg A., Pati A.,
RA Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
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DR EMBL; CP007035; AHF16547.1; -; Genomic_DNA.
DR RefSeq; WP_008587834.1; NZ_CP007035.1.
DR AlphaFoldDB; W0F0L2; -.
DR STRING; 929713.NIASO_17980; -.
DR KEGG; nso:NIASO_17980; -.
DR eggNOG; COG1472; Bacteria.
DR eggNOG; COG1680; Bacteria.
DR HOGENOM; CLU_012120_0_0_10; -.
DR OrthoDB; 9805821at2; -.
DR Proteomes; UP000003586; Chromosome.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR001466; Beta-lactam-related.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00144; Beta-lactamase; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000003586};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..975
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004788492"
FT DOMAIN 44..357
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT DOMAIN 590..952
FT /note="Beta-lactamase-related"
FT /evidence="ECO:0000259|Pfam:PF00144"
SQ SEQUENCE 975 AA; 108480 MW; BD2AD7E44B97CBB2 CRC64;
MKHCRLYIPL LALFLIPYLA TAQYKSNLSA KKWVDSVYKS LSKDQRIAQL IIVRAHSNLG
PDHIAKVTDD VKKYNVGALC FFQGGPIRQA NLTNYYQSLA KTPLMITIDG EYGLGMRLDS
VIKFPYQMTL GAMGDTSLVF EMGRAVGLQH KRLGVQVNYA PDVDINNNPN NPVIGFRSFG
EDKYKVAAMG IAYMKGMQDA GIMACAKHFP GHGDVAVDSH LDLPVINKTL DQLQELELYP
FKQLIKAGVQ SVMVGHLFVP SIDNTPHHAT SISKNAVTGL LKNTLGFNGL VFTDALEMKG
VAKYFPGNTI AVESLIAGND MLCLPESVAG TISAVNDAIK KRRLRRKDIE AKVKKVLLAK
YNLGLNQWQP VSIENLTNEL NSSTNSIRQK VAEKALTVVN LINPDGFRND FFSLPLKGKK
IAYVAFTNNE KTVLANRLQS DLNADIYYIH YNDSPGKGGS VVKNIIEGKY DAVILGFHDV
NLRKGANNYG ISQNALQNWQ VLNKENAVTM VFGNPLSLSN FCTAKSLVGA YEDDAIFQNT
AADWLESKFV ATGTLPVSVC NWKYGTGMVL KNTATGGMRP IDDARFAPID SIAEAGIQQK
AYPGCVVLAA KDGKIVFHKA FGNYEYDSTH PMQLNSIFDL ASVTKVSATT VSVMKLYEEG
KIDLKKRLED YLPWTKKTNK AKLTLEDIIL HQAGMVPFIA FYKKTLNADG SVRSDLYRSV
RSEGFTTQVA RNLYLRDDYK DTIWREILES PVIPPGQKYI YSDNDFWFLG KIVEAVTKMP
LETYVQKTFY QPMHMTTTGF HPLERFPLEA IVPTEKETHF RNQLIQGTVH DEGSALGGGV
AGHAGLFSDA YDLGKLYQML LNGGELNGHR FLKRETIQYF SAYHSSISRR GYGFDKPEKD
NATSSDPYPS KYASPQAYGH TGFTGTCVWV DPKYNIVYIF LSNRVYPTRE NPRLSSLSIR
RSILDAIYKA VVPNL
//
