ID W0HI58_9GAMM Unreviewed; 1106 AA.
AC W0HI58;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Potassium efflux system KefA protein / Small-conductance mechanosensitive channel {ECO:0000313|EMBL:AHF73436.1};
GN Name=yjeP {ECO:0000313|EMBL:AHF73436.1};
GN ORFNames=SOPEG_1104 {ECO:0000313|EMBL:AHF73436.1};
OS Candidatus Sodalis pierantonius str. SOPE.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Bruguierivoracaceae; Sodalis.
OX NCBI_TaxID=2342 {ECO:0000313|EMBL:AHF73436.1, ECO:0000313|Proteomes:UP000019025};
RN [1] {ECO:0000313|EMBL:AHF73436.1, ECO:0000313|Proteomes:UP000019025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=none {ECO:0000313|Proteomes:UP000019025};
RX PubMed=24407854; DOI=10.1093/gbe/evt210;
RA Oakeson K.F., Gil R., Clayton A.L., Dunn D.M., von Niederhausern A.C.,
RA Hamil C., Aoyagi A., Duval B., Baca A., Silva F.J., Vallier A.,
RA Jackson D.G., Latorre A., Weiss R.B., Heddi A., Moya A., Dale C.;
RT "Genome degeneration and adaptation in a nascent stage of symbiosis.";
RL Genome Biol. Evol. 6:76-93(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; CP006568; AHF73436.1; -; Genomic_DNA.
DR RefSeq; WP_025244631.1; NZ_CP006568.1.
DR AlphaFoldDB; W0HI58; -.
DR STRING; 2342.SOPEG_1104; -.
DR KEGG; pes:SOPEG_1104; -.
DR PATRIC; fig|2342.5.peg.1147; -.
DR eggNOG; COG1196; Bacteria.
DR eggNOG; COG3264; Bacteria.
DR HOGENOM; CLU_007829_2_0_6; -.
DR Proteomes; UP000019025; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049142; MS_channel_1st.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR InterPro; IPR025692; MscS_IM_dom1.
DR InterPro; IPR024393; MscS_porin.
DR PANTHER; PTHR30347:SF1; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL MSCM; 1.
DR PANTHER; PTHR30347; POTASSIUM CHANNEL RELATED; 1.
DR Pfam; PF21088; MS_channel_1st; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR Pfam; PF12795; MscS_porin; 1.
DR Pfam; PF12794; MscS_TM; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019025};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1106
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004790396"
FT TRANSMEM 479..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 520..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 554..579
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 600..620
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 632..652
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 673..694
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 700..721
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 831..851
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 872..898
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 904..933
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..259
FT /note="Mechanosensitive ion channel MscS porin"
FT /evidence="ECO:0000259|Pfam:PF12795"
FT DOMAIN 482..817
FT /note="Mechanosensitive ion channel inner membrane"
FT /evidence="ECO:0000259|Pfam:PF12794"
FT DOMAIN 878..919
FT /note="Mechanosensitive ion channel transmembrane helices
FT 2/3"
FT /evidence="ECO:0000259|Pfam:PF21088"
FT DOMAIN 921..986
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 994..1076
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
FT REGION 1086..1106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 171..245
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1106 AA; 123294 MW; EBA7A1DF481BBFEA CRC64;
MRPITLFLLG WLLASPAFAA NQPDEGQLKK ELQQAQDDKT APNQAAMVEA LQSALNALAE
GKASSAKIRE YQKAIDDFPA LTRQLRDEKD SEPDEPDPLS PKLASSELNQ RLLQANSQLM
DLAGQLQQEQ DQARAISDSL GLLPQQQTEA RRALSDVEQQ LQALPTPGTP LEQAQATALQ
AEQAARRLKV EELDLAQLSA NNRQELSRLR AELLKKRHDR VDQALQALRN QLNSLRQQEA
EQAIEHTEML AEQVGELPKS IGIPLQTNRE LSIALNQQAQ RMDLIASQQR QAASQRLQVR
QALTTLREHA QWLDESPALG ETLRTQVSRL PEMPKPQQLD SDMAQLRVQR LHFEDLMNKL
PQFAQGTQDD GSPLTPAQRR ILDAQLATQR NLLNALLTGC DTQILELTKL KVANSQLEEA
MNEIQEAAHR YLFWVADVSP IGLSYPLHVG QDLRRLVTLD TFSQLTHALG MMLTSQETLI
PLLGVLLLVG FSLSSRRHYH AFLERSSGRV GKVNQDHFSL TLRNVFWSVL VALPLPVLWA
ALGYGLRHAW PYPVAVAIGD GVSATVPVLW VFMVCAHFAR PQGLFIVHFG WPQQQVKRAL
RYYTLSIGMI VPLIMALISF DDYSEREFAG TLGRLCFLLL CACLALVTSS LKRAGLPLYL
DKHGAGDNVV NRSLWNLMIC APIIAAAAAC LGHLATAQAL LARLETSVAI WFFLLIIYHI
IRRWMFIQRR RIAFERTKQR RAEMLAQRAR NEEDLSQSQL NDAAAEVDEK VLDLDTISAQ
SLQLVRSILT LIALLSVILL WSELHSAFGF LENITLWDAT STTQGVDSIQ PITLGAVLIA
ILVFIITTQI VRNLPALLEL ALLQHLDLTP GTGYAITTLT KYGLMLLGGI IGFSMIGIEW
SKLQWLVAAL GVGLGFGLQE IFANFISGLM ILFEKPIRIG DTVTIRNLTG NITRINTRAT
TITDWDRKEI IVPNKAFITE QFVNWSLSDT ITRVVLSVPA PAGANIEQVA HILVQAARRC
PLVLELPAPE AFLVDLQQGL PLFELRMHAA EMGHRMPLRH QVHALILEGY REHGMELPFP
PFQLRKDQIK ADNTPGNRIK PESGSL
//
