ID W0HKS1_9GAMM Unreviewed; 329 AA.
AC W0HKS1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=6-phosphogluconolactonase {ECO:0000256|HAMAP-Rule:MF_01605};
DE Short=6-P-gluconolactonase {ECO:0000256|HAMAP-Rule:MF_01605};
DE EC=3.1.1.31 {ECO:0000256|HAMAP-Rule:MF_01605};
GN Name=pgl {ECO:0000256|HAMAP-Rule:MF_01605,
GN ECO:0000313|EMBL:AHF73097.1};
GN ORFNames=SOPEG_0492 {ECO:0000313|EMBL:AHF73097.1};
OS Candidatus Sodalis pierantonius str. SOPE.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Bruguierivoracaceae; Sodalis.
OX NCBI_TaxID=2342 {ECO:0000313|EMBL:AHF73097.1, ECO:0000313|Proteomes:UP000019025};
RN [1] {ECO:0000313|EMBL:AHF73097.1, ECO:0000313|Proteomes:UP000019025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=none {ECO:0000313|Proteomes:UP000019025};
RX PubMed=24407854; DOI=10.1093/gbe/evt210;
RA Oakeson K.F., Gil R., Clayton A.L., Dunn D.M., von Niederhausern A.C.,
RA Hamil C., Aoyagi A., Duval B., Baca A., Silva F.J., Vallier A.,
RA Jackson D.G., Latorre A., Weiss R.B., Heddi A., Moya A., Dale C.;
RT "Genome degeneration and adaptation in a nascent stage of symbiosis.";
RL Genome Biol. Evol. 6:76-93(2014).
CC -!- FUNCTION: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-
CC phosphogluconate. {ECO:0000256|HAMAP-Rule:MF_01605}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate
CC + H(+); Xref=Rhea:RHEA:12556, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57955, ChEBI:CHEBI:58759; EC=3.1.1.31;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01605};
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step
CC 2/3. {ECO:0000256|HAMAP-Rule:MF_01605}.
CC -!- SIMILARITY: Belongs to the cycloisomerase 2 family.
CC {ECO:0000256|ARBA:ARBA00005564, ECO:0000256|HAMAP-Rule:MF_01605}.
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DR EMBL; CP006568; AHF73097.1; -; Genomic_DNA.
DR RefSeq; WP_025244189.1; NZ_CP006568.1.
DR AlphaFoldDB; W0HKS1; -.
DR STRING; 2342.SOPEG_0492; -.
DR KEGG; pes:SOPEG_0492; -.
DR PATRIC; fig|2342.5.peg.488; -.
DR eggNOG; COG2706; Bacteria.
DR HOGENOM; CLU_038716_2_0_6; -.
DR UniPathway; UPA00115; UER00409.
DR Proteomes; UP000019025; Chromosome.
DR GO; GO:0017057; F:6-phosphogluconolactonase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR HAMAP; MF_01605; 6P_gluconolactonase; 1.
DR InterPro; IPR022528; 6-phosphogluconolactonase_YbhE.
DR InterPro; IPR019405; Lactonase_7-beta_prop.
DR InterPro; IPR011045; N2O_reductase_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR30344:SF9; 6-PHOSPHOGLUCONOLACTONASE; 1.
DR PANTHER; PTHR30344; 6-PHOSPHOGLUCONOLACTONASE-RELATED; 1.
DR Pfam; PF10282; Lactonase; 1.
DR SUPFAM; SSF50974; Nitrous oxide reductase, N-terminal domain; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277, ECO:0000256|HAMAP-
KW Rule:MF_01605};
KW Glucose metabolism {ECO:0000256|ARBA:ARBA00022526, ECO:0000256|HAMAP-
KW Rule:MF_01605};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_01605};
KW Reference proteome {ECO:0000313|Proteomes:UP000019025}.
SQ SEQUENCE 329 AA; 35254 MW; DDA28C17F516E754 CRC64;
MKHIVYVASP ESQQIHVWQM DDQGALTLLQ VVDTPGQGQP MAIHPANTHL YIGVRPAFGV
VSYRIDERGL LTEAGMAPLP GGPTQLTTDL QGTTLYSVSY SGSCLSVSPI DEQGIVGALQ
QTLKGLTHCH SANVDTTNQE LWVPCLQEDR IRRYGIGAAG RLTPLTPAAL DSVAGPRHMA
FHHGGDYAYA INELSGTVNV IAIDAAGAGP RIVQTLDIMP AGFSDTRWAA DIHITPDGRW
LYCCDRTASV ISRFAVTEDG GVLRLLGHQA TETQPRGFNI DSQGRFLVAA GQKSHHIAVY
AIEGQSGELA PLARYAVGQG PMWVSILAR
//
