ID W0HQU4_9GAMM Unreviewed; 412 AA.
AC W0HQU4;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Major facilitator superfamily transporter {ECO:0000313|EMBL:AHF76221.1};
GN ORFNames=Sant_1150 {ECO:0000313|EMBL:AHF76221.1};
OS Sodalis praecaptivus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Bruguierivoracaceae; Sodalis.
OX NCBI_TaxID=1239307 {ECO:0000313|EMBL:AHF76221.1, ECO:0000313|Proteomes:UP000019028};
RN [1] {ECO:0000313|EMBL:AHF76221.1, ECO:0000313|Proteomes:UP000019028}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HS1 {ECO:0000313|EMBL:AHF76221.1,
RC ECO:0000313|Proteomes:UP000019028};
RX PubMed=24407854; DOI=10.1093/gbe/evt210;
RA Oakeson K.F., Gil R., Clayton A.L., Dunn D.M., von Niederhausern A.C.,
RA Hamil C., Aoyagi A., Duval B., Baca A., Silva F.J., Vallier A.,
RA Jackson D.G., Latorre A., Weiss R.B., Heddi A., Moya A., Dale C.;
RT "Genome degeneration and adaptation in a nascent stage of symbiosis.";
RL Genome Biol. Evol. 6:76-93(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP006569; AHF76221.1; -; Genomic_DNA.
DR RefSeq; WP_025421350.1; NZ_CP006569.1.
DR AlphaFoldDB; W0HQU4; -.
DR KEGG; sod:Sant_1150; -.
DR PATRIC; fig|1239307.3.peg.1231; -.
DR HOGENOM; CLU_001265_57_3_6; -.
DR OrthoDB; 65739at2; -.
DR Proteomes; UP000019028; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR001958; Tet-R_TetA/multi-R_MdtG-like.
DR PANTHER; PTHR43414; MULTIDRUG RESISTANCE PROTEIN MDTG; 1.
DR PANTHER; PTHR43414:SF6; MULTIDRUG RESISTANCE PROTEIN MDTG; 1.
DR Pfam; PF07690; MFS_1; 1.
DR PRINTS; PR01035; TCRTETA.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019028};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 18..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..402
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 412 AA; 42528 MW; CBF0011862015916 CRC64;
MQNGSTAPDD NDYWRRNLVV CVFGSFTTIV AMTLLLPFLP LYVEQLGVTG HAAISEWSGV
AYGAAFFTAA LTAPLWGRLG DRYGRKLMLI RASLGMAVAM TLLGMAQSVW QLVALRLLAG
LLGGYASGST ILVATQTPKA RTGWALGMLS SGIMAGNLVG PLIGGTLPPL IGIRATFMLA
GGAIFIAFLA TVVLLKEVPG SASRPAAAAT SPAISPWRNL PVMAMLITGT LLMLANMSIE
PIITLYVAQL VSGQQVTFVA GLVMAAAALG SILSASRLGR LADRVGHWRV IIGCLLVAAV
LLIPQAFVTA GWQLVALRFC MGLALGGLLP CIASVIRHSV PAAKVGGVLG LSTSAQYVGQ
VTGPLLGGVV GGHLGMRPVF LGTCLLLAIG AGFNQLCRNA ADRSAGDVQG RP
//
