ID W0HSW9_9GAMM Unreviewed; 310 AA.
AC W0HSW9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeA {ECO:0000256|HAMAP-Rule:MF_01544};
DE Short=pHBA efflux pump protein A {ECO:0000256|HAMAP-Rule:MF_01544};
GN Name=aaeA {ECO:0000256|HAMAP-Rule:MF_01544,
GN ECO:0000313|EMBL:AHF75607.1};
GN ORFNames=Sant_0510 {ECO:0000313|EMBL:AHF75607.1};
OS Sodalis praecaptivus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Bruguierivoracaceae; Sodalis.
OX NCBI_TaxID=1239307 {ECO:0000313|EMBL:AHF75607.1, ECO:0000313|Proteomes:UP000019028};
RN [1] {ECO:0000313|EMBL:AHF75607.1, ECO:0000313|Proteomes:UP000019028}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HS1 {ECO:0000313|EMBL:AHF75607.1,
RC ECO:0000313|Proteomes:UP000019028};
RX PubMed=24407854; DOI=10.1093/gbe/evt210;
RA Oakeson K.F., Gil R., Clayton A.L., Dunn D.M., von Niederhausern A.C.,
RA Hamil C., Aoyagi A., Duval B., Baca A., Silva F.J., Vallier A.,
RA Jackson D.G., Latorre A., Weiss R.B., Heddi A., Moya A., Dale C.;
RT "Genome degeneration and adaptation in a nascent stage of symbiosis.";
RL Genome Biol. Evol. 6:76-93(2014).
CC -!- FUNCTION: Forms an efflux pump with AaeB. {ECO:0000256|HAMAP-
CC Rule:MF_01544}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_01544};
CC Single-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01544}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477, ECO:0000256|HAMAP-
CC Rule:MF_01544}.
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DR EMBL; CP006569; AHF75607.1; -; Genomic_DNA.
DR RefSeq; WP_025420737.1; NZ_CP006569.1.
DR AlphaFoldDB; W0HSW9; -.
DR KEGG; sod:Sant_0510; -.
DR PATRIC; fig|1239307.3.peg.542; -.
DR HOGENOM; CLU_018816_15_2_6; -.
DR OrthoDB; 9811754at2; -.
DR Proteomes; UP000019028; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR HAMAP; MF_01544; AaeA; 1.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR022871; PHBA_efflux_pump_AaeA.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30367:SF12; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA; 1.
DR PANTHER; PTHR30367; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA-RELATED; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_01544};
KW Membrane {ECO:0000256|HAMAP-Rule:MF_01544};
KW Reference proteome {ECO:0000313|Proteomes:UP000019028};
KW Transmembrane {ECO:0000256|HAMAP-Rule:MF_01544};
KW Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_01544};
KW Transport {ECO:0000256|HAMAP-Rule:MF_01544}.
FT DOMAIN 47..94
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
SQ SEQUENCE 310 AA; 33893 MW; 1CD1BFC70D217CF7 CRC64;
MKTFATKIVR VAITLLLVLI AAIAIFRAWS FYTESPWTRD AKFTADVVAI APDVGGLLTE
VPIRDNQQVK KGDLLLIIDK PRFQEALAQA EADVSYYQAL AAEKQREASR RRSLGTNAMS
QEQIDQASND FSTVSHQLAK AIAVRNLAKL DLARTEVRAP ADGWVTNLNV HAGEFITRGS
VAVALVKKDT FYLLAYLEET KLEGVRPGYR VEITPLGSNR ILTGTVDSIA AGVNNSSSAV
DSKGLASVDS NLEWVRLAQR VPVKIVLDKQ QGDLYPAGTT ATVVITGRRD GHPGRVSPLM
QLIHRLREFG
//
