ID W0HUN5_9GAMM Unreviewed; 871 AA.
AC W0HUN5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Nitrate reductase {ECO:0000313|EMBL:AHF77454.1};
GN Name=nasA {ECO:0000313|EMBL:AHF77454.1};
GN ORFNames=Sant_2411 {ECO:0000313|EMBL:AHF77454.1};
OS Sodalis praecaptivus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Bruguierivoracaceae; Sodalis.
OX NCBI_TaxID=1239307 {ECO:0000313|EMBL:AHF77454.1, ECO:0000313|Proteomes:UP000019028};
RN [1] {ECO:0000313|EMBL:AHF77454.1, ECO:0000313|Proteomes:UP000019028}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HS1 {ECO:0000313|EMBL:AHF77454.1,
RC ECO:0000313|Proteomes:UP000019028};
RX PubMed=24407854; DOI=10.1093/gbe/evt210;
RA Oakeson K.F., Gil R., Clayton A.L., Dunn D.M., von Niederhausern A.C.,
RA Hamil C., Aoyagi A., Duval B., Baca A., Silva F.J., Vallier A.,
RA Jackson D.G., Latorre A., Weiss R.B., Heddi A., Moya A., Dale C.;
RT "Genome degeneration and adaptation in a nascent stage of symbiosis.";
RL Genome Biol. Evol. 6:76-93(2014).
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. NasA/NapA/NarB subfamily.
CC {ECO:0000256|ARBA:ARBA00008747}.
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DR EMBL; CP006569; AHF77454.1; -; Genomic_DNA.
DR RefSeq; WP_025422600.1; NZ_CP006569.1.
DR AlphaFoldDB; W0HUN5; -.
DR KEGG; sod:Sant_2411; -.
DR PATRIC; fig|1239307.3.peg.2685; -.
DR HOGENOM; CLU_000422_13_4_6; -.
DR OrthoDB; 9810782at2; -.
DR Proteomes; UP000019028; Chromosome.
DR GO; GO:1990204; C:oxidoreductase complex; IEA:UniProt.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0045333; P:cellular respiration; IEA:UniProt.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR CDD; cd02791; MopB_CT_Nitrate-R-NapA-like; 1.
DR CDD; cd02754; MopB_Nitrate-R-NapA-like; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR007419; BFD-like_2Fe2S-bd_dom.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR041957; CT_Nitrate-R-NapA-like.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR027467; MopterinOxRdtase_cofactor_BS.
DR PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04324; Fer2_BFD; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00551; MOLYBDOPTERIN_PROK_1; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000019028}.
FT DOMAIN 1..56
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 871 AA; 94357 MW; FBEE4964E3E8F2AC CRC64;
MTRCTTCPYC GVGCGLQATP QPDGGVALSA DTHHPANRGR LCVKGAALGD TLGHEGRLLS
PQVDGAPADW GFALDSVADR LSAIIRRHGP HAVAFYASGQ LLTEDYYAAN KLMKGFIGSG
NIDTNSRLCM ASAVVGYKRA FGADAVPCCY EDLEQTQLAI VAGSNAAWAH PVAWQRLLAA
RQARPATKIV VIDPRRTASC DDADLHLPLR PGTDAALFAG LLHWLHQQGG LDPRLWPQLN
GLEATLAAAA AWTLPAVAQF CRLAEADILA FYRLFADSDR ALTLYCMGIN QSTSGSDKCN
AIINLHLASG KIGRPGCGPF SLTGQPNAMG GREVGGLANQ LACHMDFSEE NVDRLRRFWH
SERVATEPGL KAVALFEAIA RGEVKAVWIM GTNPAVSLPD GLRVRQALTG CELVVVSDVS
AKTDTTELAH ILLPAQAWGE KDGTVTNSER RISRQRRFLT PAGEARPDWW IISQVAQRMG
FASAFAWHHP AAIFREHAAL SGFENQGRRA FDISGLATVT DDEWDRLTPV QWPVNARHPQ
GQARLFGSGR CYHPDGKARL IPIQPRLPVA KPAALWPLLL NTGRTRDQWH TMTRTGLVSR
LMQHQSEPWC DIHPLDAARF GLEDGCLARI QSAQGWVVVR CRLTSSQQPG CLFVPMHWNR
QFCNMANVDQ LVAPHTCPFA GQPESKQTAV RIQRYDCDWQ GVVLARQPLT LGDAVWWSRM
PYGAVTAYWL AGSGAASDWF AALAGHAHWR YQQAQTPEVL HRLGWGDGAL QIAFYAARGA
QPVIDIPAVV AAFSDAPAPE DRLALLAGQQ ASGEAAGRTI CSCYGVGERQ IAQAIDEGCG
TVEALGKRLR CGTNCGSCIP ELKQLLARQP A
//
