ID   W0I8G2_9EURY            Unreviewed;       201 AA.
AC   W0I8G2;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Na(+) H(+) antiporter subunit E {ECO:0000313|EMBL:AHF80755.1};
GN   ORFNames=TES1_1377 {ECO:0000313|EMBL:AHF80755.1};
OS   Thermococcus paralvinellae.
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=582419 {ECO:0000313|EMBL:AHF80755.1, ECO:0000313|Proteomes:UP000019027};
RN   [1] {ECO:0000313|EMBL:AHF80755.1, ECO:0000313|Proteomes:UP000019027}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ES1 {ECO:0000313|EMBL:AHF80755.1,
RC   ECO:0000313|Proteomes:UP000019027};
RX   PubMed=25082851; DOI=10.1099/ijs.0.066100-0;
RA   Hensley S.A., Jung J.H., Park C.S., Holden J.F.;
RT   "Thermococcus paralvinellae sp. nov. and Thermococcus cleftensis sp. nov.
RT   of hyperthermophilic heterotrophs from deep-sea hydrothermal vents.";
RL   Int. J. Syst. Evol. Microbiol. 64:3655-3659(2014).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP006965; AHF80755.1; -; Genomic_DNA.
DR   RefSeq; WP_042681490.1; NZ_CP006965.1.
DR   AlphaFoldDB; W0I8G2; -.
DR   STRING; 582419.TES1_1377; -.
DR   GeneID; 24906697; -.
DR   KEGG; ths:TES1_1377; -.
DR   HOGENOM; CLU_086615_2_2_2; -.
DR   OrthoDB; 85180at2157; -.
DR   Proteomes; UP000019027; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR002758; Cation_antiport_E.
DR   PANTHER; PTHR34584; NA(+)/H(+) ANTIPORTER SUBUNIT E1; 1.
DR   PANTHER; PTHR34584:SF1; NA(+)_H(+) ANTIPORTER SUBUNIT E1; 1.
DR   Pfam; PF01899; MNHE; 1.
DR   PIRSF; PIRSF019239; MrpE; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        36..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   201 AA;  23520 MW;  D7A7FBE9C1E5923C CRC64;
     MSRVPFYLKE RLEEVHRRVL YESYDAQKLP VWERIVLTWI VLFSFWIVIT ANTSLDNLVI
     GSIATLIIAS FMRDMLMEDV RHKGHLIEKI IYFLLLYAPQ YLIIMAFRLI ESNIKVAKNV
     IFMDIKPGIV KIKTDLHSDT GITILANSIT LTPGTLTLDV SKKLGETYLY VHWIYVETLN
     REKAGEKIKG DIEEWLKKIF W
//