ID W0J671_9BACT Unreviewed; 510 AA.
AC W0J671;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Cobalamin biosynthesis protein P47K {ECO:0000313|EMBL:AHF92281.1};
GN ORFNames=OPIT5_20540 {ECO:0000313|EMBL:AHF92281.1};
OS Opitutaceae bacterium TAV5.
OC Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae.
OX NCBI_TaxID=794903 {ECO:0000313|EMBL:AHF92281.1, ECO:0000313|Proteomes:UP000003813};
RN [1] {ECO:0000313|EMBL:AHF92281.1, ECO:0000313|Proteomes:UP000003813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TAV5 {ECO:0000313|EMBL:AHF92281.1};
RX PubMed=25744998;
RA Kotak M., Isanapong J., Goodwin L., Bruce D., Chen A., Han C.S.,
RA Huntemann M., Ivanova N., Land M.L., Nolan M., Pati A., Woyke T.,
RA Rodrigues J.L.;
RT "Complete Genome Sequence of the Opitutaceae Bacterium Strain TAV5, a
RT Potential Facultative Methylotroph of the Wood-Feeding Termite
RT Reticulitermes flavipes.";
RL Genome Announc. 3:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; CP007053; AHF92281.1; -; Genomic_DNA.
DR AlphaFoldDB; W0J671; -.
DR STRING; 794903.OPIT5_20540; -.
DR KEGG; obt:OPIT5_20540; -.
DR eggNOG; COG0523; Bacteria.
DR HOGENOM; CLU_017452_0_0_0; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000003813; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000003813}.
FT DOMAIN 416..509
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 269..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..295
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 510 AA; 56008 MW; DAAAFAC6C6040F3C CRC64;
MSSAIDSAPV PATASDKAAP VPVTVLTGFL GAGKTTLLNR ILTEQHGKKL AVIENEFGEV
GVDNQLVIQS DEELFEMNNG CICCSVRGDL IRVLGRLMKR KDRLDGILIE TTGLADPGPV
AQTFFTDDEM RAAFRLDSIV TVVDAKHILL HLGDSPEVQK QIAFADVLIL NKIDLVSPDE
LDRLEARIRK MNAATRILRA RNADVPLAAV LDVGGFNLSR ASELDPRFLE PTYPFEWAGA
YALPAGKHEL VIGHPHHDHG CDCGHDHAHG HGHGHDDHDH HDHAHGEDDH GHADGHGHHH
HHHHHGNENE LDIVILPVKS LDEADLAAAR DDAVRIFADW ENKVAPGDPV TPGRTLHRLV
LDDGHGHYPL TIAQPGFHLV FEGCGEHPLH IPVMGENVRP AWQQDYEHTH SHEDAVSSVG
ITEAGTVDAQ KLNNWIGELL QKKGADIYRS KGVLSVKGSD NRLVFQGVHM LFDAKFDRPW
GKDARTNTLV FIGKDLDRDA LTKGFRSCLL
//
