ID W0JPP1_9EURY Unreviewed; 312 AA.
AC W0JPP1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Cobalamin biosynthesis protein {ECO:0000313|EMBL:AHF99144.1};
GN ORFNames=HALLA_10095 {ECO:0000313|EMBL:AHF99144.1};
OS Halostagnicola larsenii XH-48.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Halostagnicola.
OX NCBI_TaxID=797299 {ECO:0000313|EMBL:AHF99144.1, ECO:0000313|Proteomes:UP000019024};
RN [1] {ECO:0000313|EMBL:AHF99144.1, ECO:0000313|Proteomes:UP000019024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XH-48 {ECO:0000313|EMBL:AHF99144.1,
RC ECO:0000313|Proteomes:UP000019024};
RG DOE Joint Genome Institute;
RA Anderson I., Huntemann M., Han J., Chen A., Kyrpides N., Mavromatis K.,
RA Markowitz V., Palaniappan K., Ivanova N., Schaumberg A., Pati A.,
RA Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005879}.
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DR EMBL; CP007055; AHF99144.1; -; Genomic_DNA.
DR RefSeq; WP_049952353.1; NZ_CP007055.1.
DR AlphaFoldDB; W0JPP1; -.
DR STRING; 797299.HALLA_10095; -.
DR GeneID; 25144813; -.
DR KEGG; hlr:HALLA_10095; -.
DR PATRIC; fig|797299.3.peg.1048; -.
DR eggNOG; arCOG00645; Archaea.
DR HOGENOM; CLU_011276_7_1_2; -.
DR OrthoDB; 6633at2157; -.
DR Proteomes; UP000019024; Chromosome.
DR GO; GO:0046026; F:precorrin-4 C11-methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11641; Precorrin-4_C11-MT; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR006362; Cbl_synth_CobM/CibF.
DR PANTHER; PTHR45790:SF4; COBALT-PRECORRIN-4 C(11)-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR45790; SIROHEME SYNTHASE-RELATED; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000019024};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 51..256
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 293..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 312 AA; 33521 MW; 58AB598BBE7BDEE2 CRC64;
MTNTDDTGET SIATDGDDPQ QAIDAQGERR REELDERIFE HSAGDEQEGI PFVGAGPGNP
RLLTVAGKEL LGEADLVVHA GSLVNSELLE EYCAHAELVN SVGKDLEELI PLMRDAYENG
ENVVRLHSGD PAIYGAALEQ MDALEHEGVP THFVPGVTSA FAASATLRTQ LTLNEVSNHV
AFTRPQGKTL TADEDHISEF VEMGDVTTCI YLGTHAVRDT MDRLLEADHD PETPVAVIYH
ASWPDEDVII GDIGTIADKV EEAGYRASAL VVIGDAVTGA GYERSFLYGD WANRGSSESA
DENASKPEAS DD
//
