ID W0QAI2_9PAST Unreviewed; 563 AA.
AC W0QAI2;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Long-chain-fatty-acid--CoA ligase {ECO:0000256|ARBA:ARBA00039545};
DE EC=6.2.1.3 {ECO:0000256|ARBA:ARBA00026121};
DE AltName: Full=Long-chain acyl-CoA synthetase {ECO:0000256|ARBA:ARBA00042773};
GN ORFNames=X808_13820 {ECO:0000313|EMBL:AHG75904.1};
OS Mannheimia varigena USDA-ARS-USMARC-1296.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Mannheimia.
OX NCBI_TaxID=1433287 {ECO:0000313|EMBL:AHG75904.1, ECO:0000313|Proteomes:UP000066995};
RN [1] {ECO:0000313|EMBL:AHG75904.1, ECO:0000313|Proteomes:UP000066995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USDA-ARS-USMARC-1296 {ECO:0000313|EMBL:AHG75904.1,
RC ECO:0000313|Proteomes:UP000066995};
RA Harhay G.P., Clawson M.L., Murray R.W., Lubbers B.V., Heaton M.P.,
RA Chitko-Mckown C.G., Harhay D.M., Smith T.P.L.;
RT "Annotation of the Mannheimia varigena USDA-ARS-USMARC-1296 complete
RT genome.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC {ECO:0000256|ARBA:ARBA00005005}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
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DR EMBL; CP006943; AHG75904.1; -; Genomic_DNA.
DR RefSeq; WP_025217610.1; NZ_CP006943.1.
DR AlphaFoldDB; W0QAI2; -.
DR STRING; 1433287.X808_13820; -.
DR KEGG; mvi:X808_13820; -.
DR PATRIC; fig|1433287.3.peg.1384; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_9_6; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000066995; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd05936; FC-FACS_FadD_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF8; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:AHG75904.1}.
FT DOMAIN 29..420
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 470..544
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 563 AA; 63139 MW; 0A0CCF834B3445B7 CRC64;
MEKIWFNNYP PYSPKTIETN QYDSLVEMFE AAIKRHPDIP AYINMGQILT FRKLEERSRA
FAAYLQNELR LKKGDRIALM MPNLLQYPIA LFGALRAGLV IVNVNPLYTP RELEHQLNDS
GAKAIVIISN FAATLEKIVF NTNIKHVILT RMGDQLSFGK RTLVNFVVKY IKKLVPKYKL
PHAVSFREAL SIGKQRQYVK PNIINSDLAF LQYTGGTTGV AKGAMLTHQN LIANMMQAKW
IVEPLLGNTT NMIGLVPLPL YHVLALSLNC LLFIELGLTG LLITNPRDIP GFIKELKKYR
VSVITGVNTL FNALLNNDSF KEVDFSKLKL SVGGGAAIQS SVAKRWHDLT GIHIIEGYGM
TECSPLISAT RSDSVEYSGS IGVPVPNTDI RIVDDEGNDV PLGERGELLV KGPQVMQGYW
NRPEDTTEVL KDGWMATGDI VIMGEDLNLR IVDRKKDMII VSGFNVYPTE IEEVISQNPK
VNEVVAIGIP SEVSGESIKI FVTKKDESLT REELRSYCRQ FLTGYKIPRD IEFRDELPKS
NVGKILRRVL RDEELAKSPG KNS
//
