ID W0RKP4_9BACT Unreviewed; 396 AA.
AC W0RKP4;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Alcohol dehydrogenase GroES domain protein {ECO:0000313|EMBL:AHG91326.1};
GN ORFNames=J421_3789 {ECO:0000313|EMBL:AHG91326.1};
OS Gemmatirosa kalamazoonensis.
OC Bacteria; Gemmatimonadota; Gemmatimonadetes; Gemmatimonadales;
OC Gemmatimonadaceae; Gemmatirosa.
OX NCBI_TaxID=861299 {ECO:0000313|EMBL:AHG91326.1, ECO:0000313|Proteomes:UP000019151};
RN [1] {ECO:0000313|EMBL:AHG91326.1, ECO:0000313|Proteomes:UP000019151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KBS708 {ECO:0000313|EMBL:AHG91326.1,
RC ECO:0000313|Proteomes:UP000019151};
RX PubMed=24699952;
RA Debruyn J.M., Radosevich M., Wommack K.E., Polson S.W., Hauser L.J.,
RA Fawaz M.N., Korlach J., Tsai Y.C.;
RT "Genome Sequence and Methylome of Soil Bacterium Gemmatirosa
RT kalamazoonensis KBS708T, a Member of the Rarely Cultivated Gemmatimonadetes
RT Phylum.";
RL Genome Announc. 2:e00226-14(2014).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
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DR EMBL; CP007128; AHG91326.1; -; Genomic_DNA.
DR AlphaFoldDB; W0RKP4; -.
DR STRING; 861299.J421_3789; -.
DR KEGG; gba:J421_3789; -.
DR PATRIC; fig|861299.3.peg.3843; -.
DR eggNOG; COG1063; Bacteria.
DR HOGENOM; CLU_026673_11_3_0; -.
DR InParanoid; W0RKP4; -.
DR OrthoDB; 9773078at2; -.
DR Proteomes; UP000019151; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08283; FDH_like_1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000019151};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 26..149
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 196..264
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
SQ SEQUENCE 396 AA; 43532 MW; BFD503C8811471AC CRC64;
MKALCWHGVE DLRCERVPDP EIVNPRDAIV RVTSTAICGS DLHLYDGMVP SMMKGDILGH
EFMGVVEEVG RDVRNLRPGD RVLVPFAIAC GNCWYCHHDL WSLCDNSNPN AAALEALNGY
STSGLFGYSH LYGGYAGGQA EYVRVPFADV GPLKLENDLP DEKVLFLTDI FPTGYMAAEQ
CGIRPGDTVA VWGCGPVGQF AIVSAYLLGA GRVIAIDRFA ERLDMAREVG NADVVDYARD
TDDVVETLKQ MTGGRGPDHA IDAVDMESHG HGVMSRIDRG KQFLKLQLDR ADALRQAVQA
CGKGGTVSIP GVYAGFIDKF PMGQAFAKGL TLRMGQTHVH RYLRPLLERI ERGDVDPSRI
ITHRVPLERG PEMYRTFRDK QDGCVKVVLK PELRAV
//
