ID W0RMQ9_9BACT Unreviewed; 383 AA.
AC W0RMQ9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN ORFNames=J421_4215 {ECO:0000313|EMBL:AHG91752.1};
OS Gemmatirosa kalamazoonensis.
OC Bacteria; Gemmatimonadota; Gemmatimonadetes; Gemmatimonadales;
OC Gemmatimonadaceae; Gemmatirosa.
OX NCBI_TaxID=861299 {ECO:0000313|EMBL:AHG91752.1, ECO:0000313|Proteomes:UP000019151};
RN [1] {ECO:0000313|EMBL:AHG91752.1, ECO:0000313|Proteomes:UP000019151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KBS708 {ECO:0000313|EMBL:AHG91752.1,
RC ECO:0000313|Proteomes:UP000019151};
RX PubMed=24699952;
RA Debruyn J.M., Radosevich M., Wommack K.E., Polson S.W., Hauser L.J.,
RA Fawaz M.N., Korlach J., Tsai Y.C.;
RT "Genome Sequence and Methylome of Soil Bacterium Gemmatirosa
RT kalamazoonensis KBS708T, a Member of the Rarely Cultivated Gemmatimonadetes
RT Phylum.";
RL Genome Announc. 2:e00226-14(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
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DR EMBL; CP007128; AHG91752.1; -; Genomic_DNA.
DR AlphaFoldDB; W0RMQ9; -.
DR STRING; 861299.J421_4215; -.
DR KEGG; gba:J421_4215; -.
DR PATRIC; fig|861299.3.peg.4272; -.
DR eggNOG; COG0381; Bacteria.
DR HOGENOM; CLU_041674_1_0_0; -.
DR InParanoid; W0RMQ9; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000019151; Chromosome.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000019151}.
FT DOMAIN 28..366
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 383 AA; 41861 MW; B4D456EA62530C13 CRC64;
MRHRVCVVVG TRPEAIKLAP VIRALHDRRH AVECVVLATS QHREMLRQAL DAFGLRADVD
LDLMVDGQDH RQFTSRAMRA LHESFESLQP AAVMVQGDTS TVAAAALIAR ACGILLVHVE
AGLRSGSLSD PYPEELNRRI ATWAADLHFA PTERARCQLL AEGIDPESVI VTGNTVVDAL
GSFPADGPLG NARLDALPWD TQPVLLATVH RRENYGARLG QICAALRTIV ERHPAAHVVM
PVHRNPQVRQ RVHDALDGVA RVHLTEPLSY PLLLRVLRRC RLVLSDSGGL QEEVPSFHKP
ILILRDRTER PEVLDAGFGR LVGASTETIV RETSRLLTDA RLYAEMCSGR NPFGDGQAAG
RIADALIARL GARRVAIAAS RPA
//
