ID W0RN57_9BACT Unreviewed; 701 AA.
AC W0RN57;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=ATP-dependent DNA helicase, RecQ family {ECO:0000313|EMBL:AHG90878.1};
GN ORFNames=J421_3341 {ECO:0000313|EMBL:AHG90878.1};
OS Gemmatirosa kalamazoonensis.
OC Bacteria; Gemmatimonadota; Gemmatimonadetes; Gemmatimonadales;
OC Gemmatimonadaceae; Gemmatirosa.
OX NCBI_TaxID=861299 {ECO:0000313|EMBL:AHG90878.1, ECO:0000313|Proteomes:UP000019151};
RN [1] {ECO:0000313|EMBL:AHG90878.1, ECO:0000313|Proteomes:UP000019151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KBS708 {ECO:0000313|EMBL:AHG90878.1,
RC ECO:0000313|Proteomes:UP000019151};
RX PubMed=24699952;
RA Debruyn J.M., Radosevich M., Wommack K.E., Polson S.W., Hauser L.J.,
RA Fawaz M.N., Korlach J., Tsai Y.C.;
RT "Genome Sequence and Methylome of Soil Bacterium Gemmatirosa
RT kalamazoonensis KBS708T, a Member of the Rarely Cultivated Gemmatimonadetes
RT Phylum.";
RL Genome Announc. 2:e00226-14(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; CP007128; AHG90878.1; -; Genomic_DNA.
DR AlphaFoldDB; W0RN57; -.
DR STRING; 861299.J421_3341; -.
DR KEGG; gba:J421_3341; -.
DR PATRIC; fig|861299.3.peg.3393; -.
DR eggNOG; COG0514; Bacteria.
DR HOGENOM; CLU_001103_9_7_0; -.
DR InParanoid; W0RN57; -.
DR Proteomes; UP000019151; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:AHG90878.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019151}.
FT DOMAIN 35..203
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 230..376
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 622..701
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 701 AA; 77183 MW; E09EC34B74F68FF8 CRC64;
METLAVTTPT LADARRVLRR SFGYESFRLG QERAIEAVFA GRDTLVIMPT GGGKSLCYQV
PALLLPGLTV VVSPLISLMK DQVDALTARG LPAAFVNSTL TSSQANERFQ RAARGDLKLL
YVAPERFDFG NTADRLREMG VSLLAVDEAH CISEWGHDFR PSYLRMRSVR ERLGDPVTIA
LTATATPEVR DDIALQLHLR DPERIVTGFD RRNLHYHVLA VKNDAEKDAG LVQVLDRNPG
QAIVYAATRK SVERVQATLQ RAKVASVAYH AGLDDAHRHE VQDAFMNEDV RAIVATNAFG
MGIDKPNVRL VVHHAMPGSL EAYYQEAGRA GRDGNPSEVF LLHSFPDRFT HEFFIKGSYP
ERTLVEQVYG RLQRDADRAG LVTAGPQDIA LALPGKVSAR EVESALRVLS QGEALRSENE
SMSRVSVRLL ATPERIKREL SGDYNQGREL LRALWRVAGK QLETGAVIDL DGLPPGFGGG
MGAMPLLEDL QSRQFVEFER AGGGTRLTDP RRPLARFPID WTQLDRRRRA EMSKLDAMQR
YAYHTGCRRQ FVLRYFGDAA AGKTAMNCGG CDNCLGIKHE LNEPVAASTR ARKPSGGTRA
DRTERLQKAA AQREDPAELA VGPEDAGLFA GLRALRSEIA RAEQVPAYVV FPDRTLAELA
VRRPRTLAAM SAIRGVGPAK LEKYGERFLD AIRNAASVDA A
//
