ID   W0T436_KLUMD            Unreviewed;       979 AA.
AC   W0T436;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Protein CWH43 {ECO:0000313|EMBL:BAO38170.1};
GN   Name=CWH43 {ECO:0000313|EMBL:BAO38170.1};
GN   ORFNames=KLMA_10548 {ECO:0000313|EMBL:BAO38170.1};
OS   Kluyveromyces marxianus (strain DMKU3-1042 / BCC 29191 / NBRC 104275)
OS   (Yeast) (Candida kefyr).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=1003335 {ECO:0000313|EMBL:BAO38170.1, ECO:0000313|Proteomes:UP000065495};
RN   [1] {ECO:0000313|EMBL:BAO38170.1, ECO:0000313|Proteomes:UP000065495}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DMKU3-1042 / BCC 29191 / NBRC 104275
RC   {ECO:0000313|Proteomes:UP000065495};
RX   PubMed=25834639; DOI=10.1186/s13068-015-0227-x;
RA   Lertwattanasakul N., Kosaka T., Hosoyama A., Suzuki Y., Rodrussamee N.,
RA   Matsutani M., Murata M., Fujimoto N., Suprayogi, Tsuchikane K., Limtong S.,
RA   Fujita N., Yamada M.;
RT   "Genetic basis of the highly efficient yeast Kluyveromyces marxianus:
RT   complete genome sequence and transcriptome analyses.";
RL   Biotechnol. Biofuels 8:47-47(2015).
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DR   EMBL; AP012213; BAO38170.1; -; Genomic_DNA.
DR   AlphaFoldDB; W0T436; -.
DR   VEuPathDB; FungiDB:KLMA_10548; -.
DR   OrthoDB; 7379at2759; -.
DR   Proteomes; UP000065495; Chromosome 1.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR019402; Frag1/DRAM/Sfk1.
DR   PANTHER; PTHR14859; CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR; 1.
DR   PANTHER; PTHR14859:SF1; PGAP2-INTERACTING PROTEIN; 1.
DR   Pfam; PF10277; Frag1; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        94..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        118..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        149..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        302..330
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        336..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        385..404
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        411..429
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        449..468
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        489..507
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        527..545
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        575..594
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        606..629
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        641..662
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   979 AA;  112015 MW;  932D236475DDD62D CRC64;
     MVSVRGSVIA WTHTVCAASA FIAAFVVGYT LHFHKIVTNA WYSYPEEWFP SVSATIGDRY
     PERSIFQILI ALTALPRFLL LFTHYYVNRS VITLLVGIVR TVTCGGWVYI TSTDDHDIHD
     VFMISYIILT LPWDILVIRN SEHKKWKKIV MGTFFGTLVP LVYWFIQHQI HRRAGAYSIY
     AYFEWSLIIL DITFDGLAAH DFEQIKIEVS HYDNEDDKAR NTTENEFDIT FTGDLSEKSE
     VGKKNNEDSI ADISFDDQEG VVQQDRSLLL NSNDDEITIL LRETERVMYP EDLPSPPEQD
     SFMYIIVNIF NSFMFWTTLT SLFCMIWHFP LWYMGISGYE TVVIATLSPI LLYIPLANVI
     IDQYGTLLAN VLSIGAYFIE SPEDRLITVA VATALSVMTF ALNLNSLNSS TVTTFSVTWA
     LGLVLSTVVK MGFFTNNPLW AIMDETNGGL NFPGLIVSVL FALITPFTNS CHLWNKPKVQ
     TRLPYYQRIL ASMGFGSLVF AIHQSLTDAS TLIYWCWEGW SSHKGPMAWP WAALVCIVMC
     FAIVTINQSK RIMFITLALS TLLVSLPQVK EWYKFIFGVL PYTVSIIWTI PSYFQMMNYL
     QSPGLLTFSF SIYVILVLAH VWTVAYAFVP YGWLLREREP EVLFFSTILI LAGLIKFDNL
     TLFSSVTSSF LKKVKTIVVL IMILTATFTY QIRPTIVPEP YHPEANLITS GIWTIHFGFD
     NDLWASEDRM INLIKDMELD VVGLLETDTQ RITTGNRDLT AKLAHDLGMY ADFGPGPNKH
     TWGCMLLSKF PIIKSEHHLL PSPVGELAPA IHATIEAYGE LVDVFVFHSG QEEDEEDRRL
     QSEEMARLMG STDRPSILLS YLVTDPHEGN YNTYVSEKSQ MYDIDPTDED RWCEYILYKK
     LKRTGYARVS RATITDTELQ VAKFQVLHDV DQISDDDLYE YRTISSDEVP ESFKFPDKFL
     GEGERGHYYH VFDEPRYFD
//