ID   W0T4Q0_KLUMD            Unreviewed;       715 AA.
AC   W0T4Q0;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   SubName: Full=Vacuolar protein sorting-associated protein 72 {ECO:0000313|EMBL:BAO37786.1};
GN   Name=VPS72 {ECO:0000313|EMBL:BAO37786.1};
GN   ORFNames=KLMA_10164 {ECO:0000313|EMBL:BAO37786.1};
OS   Kluyveromyces marxianus (strain DMKU3-1042 / BCC 29191 / NBRC 104275)
OS   (Yeast) (Candida kefyr).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=1003335 {ECO:0000313|EMBL:BAO37786.1, ECO:0000313|Proteomes:UP000065495};
RN   [1] {ECO:0000313|EMBL:BAO37786.1, ECO:0000313|Proteomes:UP000065495}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DMKU3-1042 / BCC 29191 / NBRC 104275
RC   {ECO:0000313|Proteomes:UP000065495};
RX   PubMed=25834639; DOI=10.1186/s13068-015-0227-x;
RA   Lertwattanasakul N., Kosaka T., Hosoyama A., Suzuki Y., Rodrussamee N.,
RA   Matsutani M., Murata M., Fujimoto N., Suprayogi, Tsuchikane K., Limtong S.,
RA   Fujita N., Yamada M.;
RT   "Genetic basis of the highly efficient yeast Kluyveromyces marxianus:
RT   complete genome sequence and transcriptome analyses.";
RL   Biotechnol. Biofuels 8:47-47(2015).
CC   -!- SIMILARITY: Belongs to the VPS72/YL1 family.
CC       {ECO:0000256|ARBA:ARBA00006832}.
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DR   EMBL; AP012213; BAO37786.1; -; Genomic_DNA.
DR   AlphaFoldDB; W0T4Q0; -.
DR   VEuPathDB; FungiDB:KLMA_10164; -.
DR   OrthoDB; 2056942at2759; -.
DR   Proteomes; UP000065495; Chromosome 1.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0140849; F:ATP-dependent H2AZ histone chaperone activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   InterPro; IPR008895; Vps72/YL1.
DR   InterPro; IPR013272; Vps72/YL1_C.
DR   InterPro; IPR046757; YL1_N.
DR   PANTHER; PTHR13275:SF4; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG; 1.
DR   PANTHER; PTHR13275; YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1; 1.
DR   Pfam; PF05764; YL1; 1.
DR   Pfam; PF08265; YL1_C; 1.
DR   SMART; SM00993; YL1_C; 1.
PE   3: Inferred from homology;
FT   DOMAIN          641..670
FT                   /note="Vps72/YL1 C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00993"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          35..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          274..362
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          381..409
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        86..101
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        102..116
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        281..305
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        306..345
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        381..401
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   715 AA;  82019 MW;  5BAA75852888DDE5 CRC64;
     MSSDSEHEEL LIATRSRRAN AGNKMQKLLQ MELEEAQKRT GALDDDEINL LFQEDEEDEE
     FTLGSKKREE DEDMFSDSGD ESSGASDAEA GEHELQRQER QKRKLSQKKK NHVPVIKRAK
     TTGTQKTYKS PSDEINAESL LAVSRRTSKR SAVVANKLKV YESLTKAEKR RKLIQEKLRK
     QREKQNIRPL TQEERLKIAE ETEKFNISSL NKYKEQEISK KQTRMAMQLR EKMKFKDGEK
     IIRWISTQWE VSPLVEIEDR VYWEQYTAKR DKTKKKYVRR KKAQIEADKS RESSTSKEGT
     PIKQEEDQTS ENTVQESLEN NDEQVNVTDT QTVTNDSIKN TSAGESDNND KPEDIPSFNP
     TTKAEVVEVE EKKSINPAYV HTEESSTVDN SNIIPNSSDS NEMKNDKTEV AAEELLEDQS
     KSLPEDSYTE LPKKENETEI SFSTKPDPLK EARMNDMNSS NTSESIKHIS FAEEDQISVI
     NSEDPPILVQ TSTEVFDKSE TSSSVEQNIL EEENNEPEIK YEGPVQRVGK NFLILYTFPD
     GPFTPYPKDF KKVILGDDWL LPSKARPDEV KTITKITIAE EQEPLQCILT PDTSILDKFP
     RFGEFDKKTL RTVKMDTTKK DKIEIKTEAP TGVFLPNGIR KNCLITNKEC KYFDPKNGVP
     YSDVEAIKTI QQLQEYYDEE GEALNPRFKW FGFGRGGIFL DVLQRPAKGV PEGFI
//