ID W0T8I8_KLUMD Unreviewed; 772 AA.
AC W0T8I8;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Chromosome transmission fidelity protein 18 {ECO:0000313|EMBL:BAO39348.1};
GN Name=CTF18 {ECO:0000313|EMBL:BAO39348.1};
GN ORFNames=KLMA_30053 {ECO:0000313|EMBL:BAO39348.1};
OS Kluyveromyces marxianus (strain DMKU3-1042 / BCC 29191 / NBRC 104275)
OS (Yeast) (Candida kefyr).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=1003335 {ECO:0000313|EMBL:BAO39348.1, ECO:0000313|Proteomes:UP000065495};
RN [1] {ECO:0000313|EMBL:BAO39348.1, ECO:0000313|Proteomes:UP000065495}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DMKU3-1042 / BCC 29191 / NBRC 104275
RC {ECO:0000313|Proteomes:UP000065495};
RX PubMed=25834639; DOI=10.1186/s13068-015-0227-x;
RA Lertwattanasakul N., Kosaka T., Hosoyama A., Suzuki Y., Rodrussamee N.,
RA Matsutani M., Murata M., Fujimoto N., Suprayogi, Tsuchikane K., Limtong S.,
RA Fujita N., Yamada M.;
RT "Genetic basis of the highly efficient yeast Kluyveromyces marxianus:
RT complete genome sequence and transcriptome analyses.";
RL Biotechnol. Biofuels 8:47-47(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the activator 1 small subunits family. CTF18
CC subfamily. {ECO:0000256|ARBA:ARBA00043975}.
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DR EMBL; AP012215; BAO39348.1; -; Genomic_DNA.
DR AlphaFoldDB; W0T8I8; -.
DR VEuPathDB; FungiDB:KLMA_30053; -.
DR OrthoDB; 6297at2759; -.
DR Proteomes; UP000065495; Chromosome 3.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR23389; CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; 1.
DR PANTHER; PTHR23389:SF3; CHROMOSOME TRANSMISSION FIDELITY PROTEIN 18 HOMOLOG; 1.
DR Pfam; PF00004; AAA; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 184..339
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 75..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 155..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 279..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 512..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 678..741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 678..695
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..726
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 772 AA; 85265 MW; CB806162EA0F001D CRC64;
MPAPLPTFTA RASDSVLQVH EFDPSAKRFV SASGQTVSLR KRKPAHAALV EGQTTWTSDE
SYGVNVNTLL DRIEGGTPLE RPADTPANES SGLANGKASG KASASANASA NGTLWTEKWR
PHKFLDLVGN EHTNRRILAW LRQWAPTVFD EPLPDALPNA SGNGNGNASG ADDTTPMDPL
GRPTKRILLI HGPPGVGKTS VSHVVARQAG YSVVEINASD ERAGERVRLK VQNALFNHTF
NSKPVCLVAD EIDGSVENGF IRVLLDIIKS DSNATKEMVL GGGGRARGKA RARGKSQGKN
KNKNQLLTRP IVAICNNLYA PALEKLRPHC EIIAFRKPSE TALLERLELV CKTERVPVSK
AYLKDLAVLS QGDVRNCLNN LQFRARATTS TGTTSSGPDD GKDIAISWYR ICNSVFRKNP
HMEPEVQLSH LLKDVETSGN HERVVEGCWT MYPETRYSDH GVSKPARISD WLFFHDRMFQ
SLFEHNGELV RYCSFTPLQF FVLFADNANK EGTNNNNGRS RDGGTTTTSP GGVTSLFELR
EAERACMNLL DVVRSRLSVH SQVYTTKRSL LGETLPAVED LISVDLSRIR DVPTRQRCVD
TVLPLFHDFR LRIQEQTQGS INSSSSYTHL LVVDPPLDEL VLMDEKRRRD VVTKKPAALK
FSLAKLEEER IKKRALKAVA DEKREQSEQK RRRMEAGTSG GATGTTTGTS TSTSTSTGNF
MEQYNSIKKR EVTPEAKDTA SESRIWVKYK EGFSNAVRKN VTWSQLWEGP GS
//
