ID   W0TBT1_KLUMD            Unreviewed;       861 AA.
AC   W0TBT1;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   SubName: Full=Importin subunit beta-1 {ECO:0000313|EMBL:BAO40845.1};
GN   Name=KAP95 {ECO:0000313|EMBL:BAO40845.1};
GN   ORFNames=KLMA_50191 {ECO:0000313|EMBL:BAO40845.1};
OS   Kluyveromyces marxianus (strain DMKU3-1042 / BCC 29191 / NBRC 104275)
OS   (Yeast) (Candida kefyr).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=1003335 {ECO:0000313|EMBL:BAO40845.1, ECO:0000313|Proteomes:UP000065495};
RN   [1] {ECO:0000313|EMBL:BAO40845.1, ECO:0000313|Proteomes:UP000065495}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DMKU3-1042 / BCC 29191 / NBRC 104275
RC   {ECO:0000313|Proteomes:UP000065495};
RX   PubMed=25834639; DOI=10.1186/s13068-015-0227-x;
RA   Lertwattanasakul N., Kosaka T., Hosoyama A., Suzuki Y., Rodrussamee N.,
RA   Matsutani M., Murata M., Fujimoto N., Suprayogi, Tsuchikane K., Limtong S.,
RA   Fujita N., Yamada M.;
RT   "Genetic basis of the highly efficient yeast Kluyveromyces marxianus:
RT   complete genome sequence and transcriptome analyses.";
RL   Biotechnol. Biofuels 8:47-47(2015).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the importin beta family. Importin beta-1
CC       subfamily. {ECO:0000256|ARBA:ARBA00010907}.
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DR   EMBL; AP012217; BAO40845.1; -; Genomic_DNA.
DR   AlphaFoldDB; W0TBT1; -.
DR   VEuPathDB; FungiDB:KLMA_50191; -.
DR   OrthoDB; 124901at2759; -.
DR   Proteomes; UP000065495; Chromosome 5.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   PANTHER; PTHR10527:SF1; IMPORTIN SUBUNIT BETA-1; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
FT   DOMAIN          25..106
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
SQ   SEQUENCE   861 AA;  95347 MW;  030AC9D32DDE533E CRC64;
     MSASEVAQFL ENIIVTPDPT VRLQAETTLK KLSNDNFLQF AGLLSQILAD SSVRLEARIL
     AGLTLKNELI SKNPTKAQQF AQRWSTQIDP DSRHHIKQFT LQALVDPETR VANAAAQLIA
     AIAEIELPLN QWPELMKIMV DNTAQDQPEN VKRASLLALG YICESANQSD ETLINQSNNI
     LIAIVQGAQS NEPSKVVRLT ALNALADSLA FIKNNMEREG ERNYLMQVVC EATQAQDEDI
     QAAAFGCLCK IMSLYYFYMK PYMEQALFAL TVATMQSSNE KVAAMAVEFW STICEEEIDI
     AFELSQYSNP GLESYNFALV SIQEVVPTLL QLLTKQNEDP DDDDWNVAMS AGACLQLFAQ
     NCGNFVVAPV LNFVEQNITS DNWRQREAAV MAFGSILDGP DKTQLTSLVH QALPPILNLI
     NDPVLQVKET VAWCIGRIAD SVVAAIDPQE HLSDVINACL IGLKDHPKVA TNCSWTIINL
     VEQLADTPSS PIYNYYPVLV SALLEASNRT DNEHNARASV FSALTSLVEF ANDQVGETTT
     SISTFVLDKL GQTMQVDEAQ LTAEDRQNLH ELQSNILSVL AAVIRKNPQS VNPVADMLMD
     LFMKLLSKSD TTYVEDDVFY AISALASALG KQFQKYLETF SPYLVNALNQ VQSQVCITAV
     NLIADISNSL EDDFKRFAPS FMNVLGQMLS SPDAKKELQP AVLSVFGDIA TNIGSDFVPY
     LSQVMSVCVI AQNYKPNYNS SDALDYQYKL YESILDAYVG IITGLHDQPD ALFPYTGSIF
     QFINLLADNP SVSLEESIAR TAVGIVGDIA AMYPDGRLKQ FYTQPWMTKF IKDVKSNQSF
     AQTTRDTARW AREQQKLQSN L
//