ID W0TD45_KLUMD Unreviewed; 484 AA.
AC W0TD45;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Sec sixty-one protein homolog {ECO:0000313|EMBL:BAO40741.1};
GN Name=SSH1 {ECO:0000313|EMBL:BAO40741.1};
GN ORFNames=KLMA_50087 {ECO:0000313|EMBL:BAO40741.1};
OS Kluyveromyces marxianus (strain DMKU3-1042 / BCC 29191 / NBRC 104275)
OS (Yeast) (Candida kefyr).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=1003335 {ECO:0000313|EMBL:BAO40741.1, ECO:0000313|Proteomes:UP000065495};
RN [1] {ECO:0000313|EMBL:BAO40741.1, ECO:0000313|Proteomes:UP000065495}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DMKU3-1042 / BCC 29191 / NBRC 104275
RC {ECO:0000313|Proteomes:UP000065495};
RX PubMed=25834639; DOI=10.1186/s13068-015-0227-x;
RA Lertwattanasakul N., Kosaka T., Hosoyama A., Suzuki Y., Rodrussamee N.,
RA Matsutani M., Murata M., Fujimoto N., Suprayogi, Tsuchikane K., Limtong S.,
RA Fujita N., Yamada M.;
RT "Genetic basis of the highly efficient yeast Kluyveromyces marxianus:
RT complete genome sequence and transcriptome analyses.";
RL Biotechnol. Biofuels 8:47-47(2015).
CC -!- SIMILARITY: Belongs to the SecY/SEC61-alpha family.
CC {ECO:0000256|RuleBase:RU004349}.
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DR EMBL; AP012217; BAO40741.1; -; Genomic_DNA.
DR AlphaFoldDB; W0TD45; -.
DR VEuPathDB; FungiDB:KLMA_50087; -.
DR OrthoDB; 166798at2759; -.
DR Proteomes; UP000065495; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:InterPro.
DR Gene3D; 1.10.3370.10; SecY subunit domain; 1.
DR InterPro; IPR002208; SecY/SEC61-alpha.
DR InterPro; IPR023201; SecY_dom_sf.
DR InterPro; IPR019561; Translocon_Sec61/SecY_plug_dom.
DR PANTHER; PTHR10906:SF5; SEC SIXTY-ONE PROTEIN HOMOLOG; 1.
DR PANTHER; PTHR10906; SECY/SEC61-ALPHA FAMILY MEMBER; 1.
DR Pfam; PF10559; Plug_translocon; 1.
DR Pfam; PF00344; SecY; 1.
DR PIRSF; PIRSF004557; SecY; 1.
DR SUPFAM; SSF103491; Preprotein translocase SecY subunit; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 78..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..74
FT /note="Translocon Sec61/SecY plug"
FT /evidence="ECO:0000259|Pfam:PF10559"
SQ SEQUENCE 484 AA; 52247 MW; A620C9FD4F0BF088 CRC64;
MAGFCLIDLA KPFMAFLPEI EIPYENLPFD EKVVFTLTTA LIYLFSQFPL AGISKESVAV
KDPIFFLRGV FAAEPKTLLE FGIFPPVATA LILQLLAGFK TIKVNFNQRT DRELFQTLTK
VISIATYAIL ANIFIASGYY GENLSLMAKL LINAQLIGAG FFITLLVEVV DKGHGFASGS
MSIVAISLST SLVDDLFGIQ QFPVDQEGHT EPRGAIINLL QGLRAKHKTF TGAIVNAFQR
DYLPNLTSGL LVIVIGAAIC YLQNVRNELS IRSTKARGMT NIYPIKLLYT GGLSVLFSYS
LLFYIHILAF AVIQLIGGNK DGSIINKLFG GYQATEFFYV PRFPLSLLAP PTSLAALITQ
PLSLITFPAF LIVTGVWFAT NWQDISGSSA RDVGKQFKEQ DVALAGHRDA SKELIRIIPV
ASATGAAALA ALVSVGELLG LKGKAAGIVV AVTSVFAILE IVTVEFQQNG SQSTIAQMLG
GRVA
//
