ID W0TJY0_KLUMD Unreviewed; 582 AA.
AC W0TJY0;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=6-phosphofructo-2-kinase/fructose-2 {ECO:0000313|EMBL:BAO42464.1};
GN Name=PFK26 {ECO:0000313|EMBL:BAO42464.1};
GN ORFNames=KLMA_80153 {ECO:0000313|EMBL:BAO42464.1};
OS Kluyveromyces marxianus (strain DMKU3-1042 / BCC 29191 / NBRC 104275)
OS (Yeast) (Candida kefyr).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=1003335 {ECO:0000313|EMBL:BAO42464.1, ECO:0000313|Proteomes:UP000065495};
RN [1] {ECO:0000313|EMBL:BAO42464.1, ECO:0000313|Proteomes:UP000065495}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DMKU3-1042 / BCC 29191 / NBRC 104275
RC {ECO:0000313|Proteomes:UP000065495};
RX PubMed=25834639; DOI=10.1186/s13068-015-0227-x;
RA Lertwattanasakul N., Kosaka T., Hosoyama A., Suzuki Y., Rodrussamee N.,
RA Matsutani M., Murata M., Fujimoto N., Suprayogi, Tsuchikane K., Limtong S.,
RA Fujita N., Yamada M.;
RT "Genetic basis of the highly efficient yeast Kluyveromyces marxianus:
RT complete genome sequence and transcriptome analyses.";
RL Biotechnol. Biofuels 8:47-47(2015).
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DR EMBL; AP012220; BAO42464.1; -; Genomic_DNA.
DR AlphaFoldDB; W0TJY0; -.
DR VEuPathDB; FungiDB:KLMA_80153; -.
DR OrthoDB; 2013830at2759; -.
DR Proteomes; UP000065495; Chromosome 8.
DR GO; GO:0003873; F:6-phosphofructo-2-kinase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
DR GO; GO:0006000; P:fructose metabolic process; IEA:InterPro.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR003094; 6Pfruct_kin.
DR InterPro; IPR013079; 6Phosfructo_kin.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10606:SF32; 6-PHOSPHOFRUCTO-2-KINASE 1; 1.
DR PANTHER; PTHR10606; 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE; 1.
DR Pfam; PF01591; 6PF2K; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR PRINTS; PR00991; 6PFRUCTKNASE.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:BAO42464.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000313|EMBL:BAO42464.1}.
FT DOMAIN 2..184
FT /note="6-phosphofructo-2-kinase"
FT /evidence="ECO:0000259|Pfam:PF01591"
FT REGION 439..480
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 548..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 582 AA; 66812 MW; FA8F799C7246CAE5 CRC64;
MYYCKVFNVG NTRRQFAKEH NMKEQDSKFF DPNDEHSKML REKWAMDTLD QLLDYLLKGP
GSVGIFDATN STRERRKKIL QKIHEKNKFI KVLYLESICS DKETVEKNIR LKLLGPDYKG
KDPDSSLIDF KERLSNYMKS YQTIEDDENV PYIKMIDIGK KIVSYDIQGF LASQTVYYLL
NFNLAERQIW ISRSGESEFN VQGRIGGDSL LTQRGWKYAK ALARFMEEQK KLFNERQMKE
HLKVCSDEGS KRDFTPTEFF VWTSMKKRAM ATSSTFNDAH FDIKQMKMLD ELSAGDFEGM
TYEEILRNHP AEYEERLEDK LRYRYPGIGG ESYMDVINRL RPVITEIERI TDSLLLITHR
VVARVLLGYF LNLSKDVISN LDVPLHSVYC LEPKPYGVSW YLYEYDEEKD TFFKVPQSEL
NTMKVKEVGL VHQERRYSII PTAPSTGGKS RSGSHSSNNT SSSSTAASSA RMPSFNPPFS
ASAHMNAASR FIHPGRQHPA YQTHPSLLAR TMSRNHSSDH VGIIKKSVSP RELSNSIELD
KLNEKLSKLA SSDESKNGES DDTPAGVPLT RSQSESYSPK AS
//
