ID W1DLX9_KLEPN Unreviewed; 610 AA.
AC W1DLX9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Lysine decarboxylase 2, constitutive {ECO:0000313|EMBL:CDL09807.1};
DE EC=4.1.1.18 {ECO:0000313|EMBL:CDL09807.1};
OS Klebsiella pneumoniae IS43.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=1432552 {ECO:0000313|EMBL:CDL09807.1, ECO:0000313|Proteomes:UP000019183};
RN [1] {ECO:0000313|EMBL:CDL09807.1, ECO:0000313|Proteomes:UP000019183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IS43 {ECO:0000313|EMBL:CDL09807.1,
RC ECO:0000313|Proteomes:UP000019183};
RA Barisic I., Mitteregger D., Hirschl A.M., Noehammer C., Wiesinger-Mayr H.;
RT "Antibiotic resistance diversity of beta-lactamase producers in the General
RT Hospital Vienna.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDL09807.1}.
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DR EMBL; CBWK010000405; CDL09807.1; -; Genomic_DNA.
DR AlphaFoldDB; W1DLX9; -.
DR eggNOG; COG1982; Bacteria.
DR Proteomes; UP000019183; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0008923; F:lysine decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR CDD; cd00615; Orn_deC_like; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR005308; OKR_de-COase_N.
DR InterPro; IPR011193; Orn/lys/arg_de-COase.
DR InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR45229:SF3; BIODEGRADATIVE ARGININE DECARBOXYLASE; 1.
DR PANTHER; PTHR45229; CONSTITUTIVE ORNITHINE DECARBOXYLASE; 1.
DR Pfam; PF01276; OKR_DC_1; 1.
DR Pfam; PF03709; OKR_DC_1_N; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00703; OKR_DC_1; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:CDL09807.1}.
FT DOMAIN 362..376
FT /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT attachment site"
FT /evidence="ECO:0000259|PROSITE:PS00703"
FT REGION 567..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 610 AA; 68059 MW; 27BC76347F6B1D14 CRC64;
MNIIAIMGPH GVYHKDEPIK ELEAALQRQG FQTIWPQNSA DLLQFIEHNP RICGVIFDWD
EYSVDLCSDI NQLNEYLPLY AFINAHSTMD VSSQDLRMTL WFFEYALGLS EEIATRIGQY
TREYLENITP PFTRALFNYV QEGKYTFCTP GHMGGSAYQK SPVGCLFYDF FGGNTLKADV
SISVTELGSL LDHTGPHLEA EEYIARAFGA EQSYMVTNGT STSNKIVGMY SAPAGSTLLI
DRNCHKSLAH LLMMSDVVPL WLKPTRNALG ILGGIPRREF TRDSIQQKVR DTGGAQWPVH
AVITNSTYDG LLYNTTWLKE TLDVPSIHFD SAWVPYTHFH PIYQGKSGMS GERIPGKVIF
ETQSTHKMLA ALSQASLIHI KGNYDEETFN EAFMMHTSTS PSYPIVASIE TAAAMLRGNS
GKRLIQRSIE RALDFRKEVQ RLREESDGWF FDIWQPEAVD KAECWPVAPG EDWHGFKDAD
ADHMYLDPVK VTILTPGMDE QGNMDEEGIP AALVAKFLDE RGVVVEKTGP YNLLFLFSIG
IDKTRAMGLL RGLTEFKTRL RSQSAGEKYA AGSVRRRSRL LPQHADPGSG AGDPPLDPSA
SAAAADAQRL
//
