ID W1DWG9_KLEPN Unreviewed; 481 AA.
AC W1DWG9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Altronate oxidoreductase {ECO:0000313|EMBL:CDL13070.1};
DE EC=1.1.1.58 {ECO:0000313|EMBL:CDL13070.1};
OS Klebsiella pneumoniae IS43.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=1432552 {ECO:0000313|EMBL:CDL13070.1, ECO:0000313|Proteomes:UP000019183};
RN [1] {ECO:0000313|EMBL:CDL13070.1, ECO:0000313|Proteomes:UP000019183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IS43 {ECO:0000313|EMBL:CDL13070.1,
RC ECO:0000313|Proteomes:UP000019183};
RA Barisic I., Mitteregger D., Hirschl A.M., Noehammer C., Wiesinger-Mayr H.;
RT "Antibiotic resistance diversity of beta-lactamase producers in the General
RT Hospital Vienna.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDL13070.1}.
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DR EMBL; CBWK010000888; CDL13070.1; -; Genomic_DNA.
DR AlphaFoldDB; W1DWG9; -.
DR Proteomes; UP000019183; Unassembled WGS sequence.
DR GO; GO:0009026; F:tagaturonate reductase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR013118; Mannitol_DH_C.
DR InterPro; IPR013131; Mannitol_DH_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR30524:SF0; ALTRONATE OXIDOREDUCTASE-RELATED; 1.
DR PANTHER; PTHR30524; MANNITOL-1-PHOSPHATE 5-DEHYDROGENASE; 1.
DR Pfam; PF01232; Mannitol_dh; 1.
DR Pfam; PF08125; Mannitol_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CDL13070.1}.
FT DOMAIN 17..172
FT /note="Mannitol dehydrogenase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01232"
FT DOMAIN 204..455
FT /note="Mannitol dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08125"
SQ SEQUENCE 481 AA; 54381 MW; 7C1375C132138CD0 CRC64;
MKTLNRQNFP GPQYPTRAIQ FGEGNFLRAF IDWQLDLLNE KTDLATGVTI VRPINTVFPP
SLNTQDGLYT TVIRGLNERG EAVSEARIIR SVNNEINPWQ DFAGYLALAR DPEITFVFSN
TTEAGISYHA GDRPDDMPPV SFPAKLTQLL LERFRHFNGA ADKGWTIIPC ELIDYNGEAL
KALVLRYAKE WQLPTAFSDW VETANTFCST LVDRIVTGYP REEAEKLEAE LGYHDAFLDT
AEYFWLFVIQ GPQGLAEMLR LDRCPLNIRI VEDIRPYKAR KVAILNGAHT ALVPVAWLCG
VDTVGEAMRD KAVRHYVQQT IDEEIIPALD LPAEELRQFA DAVTGRFLNP YIRHQLLAIA
LNGMTKFRTR ILPQLLTTIR QHGAIPPRLT FALAALIAFY RGQRDGQTYP LQDDEVWLTR
FAEGWAQVAN GSPLHELVTE VLQDAAHWGE DLTAIPCLAD QVTRYLEMIL RAGMREALSR
L
//
