ID   W1J0I2_9GAMM            Unreviewed;      1001 AA.
AC   W1J0I2;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Multidrug resistance protein mdtC {ECO:0000313|EMBL:CDL84237.1};
GN   Name=mdtC {ECO:0000313|EMBL:CDL84237.1};
GN   ORFNames=XSR1_420004 {ECO:0000313|EMBL:CDL84237.1};
OS   Xenorhabdus szentirmaii DSM 16338.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=1427518 {ECO:0000313|EMBL:CDL84237.1, ECO:0000313|Proteomes:UP000019202};
RN   [1] {ECO:0000313|EMBL:CDL84237.1, ECO:0000313|Proteomes:UP000019202}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16338 {ECO:0000313|EMBL:CDL84237.1,
RC   ECO:0000313|Proteomes:UP000019202};
RA   Gualtieri M., Ogier J.C., Pages S., Givaudan A., Gaudriault S.;
RT   "Draft genome sequence and annotation of the entomopathogenic bacteria,
RT   Xenorhabdus cabanillasi strain JM26 and Xenorhabdus szentirmai strain DSM
RT   16338.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDL84237.1}.
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DR   EMBL; CBXF010000102; CDL84237.1; -; Genomic_DNA.
DR   AlphaFoldDB; W1J0I2; -.
DR   STRING; 1427518.XSR1_420004; -.
DR   Proteomes; UP000019202; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF34; MULTIDRUG RESISTANCE PROTEIN MDTC; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019202};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        304..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        327..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        358..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        398..418
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        430..457
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        825..843
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        876..901
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        921..942
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        954..980
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1001 AA;  109181 MW;  55BDBACED72AA479 CRC64;
     MAPLPQVDYP QITVSASMPG ASPETMASSV TTPLERSLVR ISGVKVMSSY SLLGSSYISL
     QFDLSRDTNS AARDVQAAIN AAQNMLPSGM PSKPGYYKAN LSGAPIMLLT LTSNDYSQGQ
     LYDLASSRLE QKLSQIEGVS QVNVRGGSLP AIRVELNPNA LFNQGISLND VSSAINAANV
     RRPMGYVDSD QHSWQLQTND ELKTVDGYRS VIIRHNNGAP VRLQDVANIK YSVEDVRAAA
     MSSTKSAIAI IIRREAGANI IATIQRIRDE LPHLKASLPA SVQLNIAQDR SPGIKASLQE
     VEQALAIAVG LVILVVFLFL RSGRATLIPA VAVPVSLIGT FTALYLCDLS LNNLSLMALT
     IATGFVVDDA IVVLENISRH LDAGIKPMQA ALKGVREVGF TVLAMSLSLV AVFIPLVLID
     ELLARLFQDF AVTLATAIGI SLLVSLTLTP MMCAHLLKSS PARAQKQRRG FGKVLSGIQQ
     IYARSLKWVL NHTRWVLFTL LGIIALNIWL YSSIPKSFFP RQDTGSMLGY VVADQSISFQ
     AMHEKMKYFM QVIDSDPTVA NVAGFTDGDS NNTSYMFISL KPRKERSENI QQVITRLRKE
     LGNTSGANLY LIAIQDLPSG GGGGREGKGS YQFSLLSDDF GELRKWGPII KKALEKSPQL
     VDVNSDADSE NKGAEIAITY DRDVMARLGI NVADANSLLY NAFGQRQIST IYQPLNQYKV
     VMEVEPQYTR DPSALEKMFV INGKGERIPL SYFSQWRPAN APLEVYHQGL SASSTIAFDV
     APGYTLSDAM NAIEKTMTEL SVPSSVRSSF TGSAQDFQES ERSQLIVLLA AIVTVYLVLG
     VLYESYLHPL TILSTLPSAG VGALLALELF NTPFSLIAMI GIMLLIGLVK KNAIIMVDFA
     LKAQRNSNIN AQDAIFQACL LRFRPIMMTT LSAILGAVPL VLNNGDGAEL RFPLGITIVG
     GLIMSQLLTL YTTPVVYLFF DRLREKWYQR RTAKCHTTPL R
//