ID W1J5Z8_9GAMM Unreviewed; 591 AA.
AC W1J5Z8;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Acetyl-/propionyl-coenzyme A carboxylase alpha chain {ECO:0000313|EMBL:CDL86149.1};
DE EC=6.3.4.14 {ECO:0000313|EMBL:CDL86149.1};
GN Name=bccA {ECO:0000313|EMBL:CDL86149.1};
GN ORFNames=XCR1_2770004 {ECO:0000313|EMBL:CDL86149.1};
OS Xenorhabdus cabanillasii JM26.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=1427517 {ECO:0000313|EMBL:CDL86149.1, ECO:0000313|Proteomes:UP000019197};
RN [1] {ECO:0000313|EMBL:CDL86149.1, ECO:0000313|Proteomes:UP000019197}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JM26 {ECO:0000313|EMBL:CDL86149.1,
RC ECO:0000313|Proteomes:UP000019197};
RA Gualtieri M., Ogier J.C., Pages S., Givaudan A., Gaudriault S.;
RT "Draft genome sequence and annotation of the entomopathogenic bacterium,
RT Xenorhabdus cabanillasi strain JM26.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=biotin; Xref=ChEBI:CHEBI:57586;
CC Evidence={ECO:0000256|ARBA:ARBA00001953};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDL86149.1}.
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DR EMBL; CBXE010000198; CDL86149.1; -; Genomic_DNA.
DR RefSeq; WP_038265316.1; NZ_NJGH01000056.1.
DR AlphaFoldDB; W1J5Z8; -.
DR OrthoDB; 9763189at2; -.
DR Proteomes; UP000019197; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004075; F:biotin carboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR005481; BC-like_N.
DR InterPro; IPR011764; Biotin_carboxylation_dom.
DR InterPro; IPR005482; Biotin_COase_C.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR011054; Rudment_hybrid_motif.
DR InterPro; IPR011053; Single_hybrid_motif.
DR PANTHER; PTHR48095:SF2; BIOTIN CARBOXYLASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR48095; PYRUVATE CARBOXYLASE SUBUNIT A; 1.
DR Pfam; PF02785; Biotin_carb_C; 1.
DR Pfam; PF00289; Biotin_carb_N; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF02786; CPSase_L_D2; 1.
DR SMART; SM00878; Biotin_carb_C; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR SUPFAM; SSF51246; Rudiment single hybrid motif; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS50979; BC; 1.
DR PROSITE; PS00867; CPSASE_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Biotin {ECO:0000256|ARBA:ARBA00023267};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:CDL86149.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00409}.
FT DOMAIN 11..455
FT /note="Biotin carboxylation"
FT /evidence="ECO:0000259|PROSITE:PS50979"
FT DOMAIN 130..327
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
SQ SEQUENCE 591 AA; 64465 MW; B045BD15B5426A45 CRC64;
MNATVNNVKK TTNKALIANR GEIAVRIIRA CRDYGIQTVA VYADSDFDAQ HVQLADEAYA
LAGNRPTETY LNIPRLLEIA KQAQATMIHP GYGFLSERAE FARAVIDAGL IWIGPDPDTI
DELGNKVKAR KIARQVGAPL VTGTTEPVKD VQEVVAFAGE HGLPIAIKAA FGGGGRGLKV
AWRRDEVEEL YYSAVREATA AFGRGECFIE QFLNKPRHIE AQVIADKYGN IVVVGTRDCS
LQRRNQKLVE EAPAPFLTQQ QRERIHQAAK EICAATHYVG AGTVEFLLSA NGTLSFLEVN
TRLQVEHPVT EETTGIDLVI EQLRIAEGYP LSIQETPAPR GHSFEFRINA EDAGKGFLPT
SGTITEFLPP SGPGIRLDSG VMSGSTIPAT FDSLMAKLIV TGTTREQALA RARRALQEFK
ISGVASVLPF HRAVIEHSDF VSGDNFNVHT RWIETDFANK LEASLRQIPA EDKNITRTYI
EIDGRRCELG LPSALLAGLA HSLPANGQQL LLPITEEAEP KDPRQVKASI SGILHSWLVQ
EGEQVNEGNV IAVMEAMKME VQISAHCSGK ITFCAQAGNY QDAESILASI E
//
