ID W1JBP2_9GAMM Unreviewed; 812 AA.
AC W1JBP2;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Putative P4-specific DNA primase {ECO:0000313|EMBL:CDL86930.1};
GN Name=Alpha {ECO:0000313|EMBL:CDL86930.1};
GN ORFNames=XCR1_800025 {ECO:0000313|EMBL:CDL86930.1};
OS Xenorhabdus cabanillasii JM26.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=1427517 {ECO:0000313|EMBL:CDL86930.1, ECO:0000313|Proteomes:UP000019197};
RN [1] {ECO:0000313|EMBL:CDL86930.1, ECO:0000313|Proteomes:UP000019197}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JM26 {ECO:0000313|EMBL:CDL86930.1,
RC ECO:0000313|Proteomes:UP000019197};
RA Gualtieri M., Ogier J.C., Pages S., Givaudan A., Gaudriault S.;
RT "Draft genome sequence and annotation of the entomopathogenic bacterium,
RT Xenorhabdus cabanillasi strain JM26.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDL86930.1}.
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DR EMBL; CBXE010000476; CDL86930.1; -; Genomic_DNA.
DR AlphaFoldDB; W1JBP2; -.
DR OrthoDB; 784829at2; -.
DR Proteomes; UP000019197; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:1990077; C:primosome complex; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003896; F:DNA primase activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd01029; TOPRIM_primases; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR Gene3D; 3.90.580.10; Zinc finger, CHC2-type domain; 1.
DR InterPro; IPR004968; DNA_primase/NTPase_C.
DR InterPro; IPR036977; DNA_primase_Znf_CHC2.
DR InterPro; IPR014015; Helicase_SF3_DNA-vir.
DR InterPro; IPR045455; NrS-1_pol-like_helicase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014818; Phage/plasmid_primase_P4_C.
DR InterPro; IPR013237; Phage_T7_Gp4_N.
DR InterPro; IPR034154; TOPRIM_DnaG/twinkle.
DR InterPro; IPR006171; TOPRIM_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR35372; ATP BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR35372:SF2; SF3 HELICASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08706; D5_N; 1.
DR Pfam; PF19263; DUF5906; 1.
DR Pfam; PF03288; Pox_D5; 1.
DR Pfam; PF08273; Prim_Zn_Ribbon; 1.
DR Pfam; PF13362; Toprim_3; 1.
DR SMART; SM00885; D5_N; 1.
DR SMART; SM00778; Prim_Zn_Ribbon; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS51206; SF3_HELICASE_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Primosome {ECO:0000256|ARBA:ARBA00022515};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 507..660
FT /note="SF3 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51206"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 812 AA; 89666 MW; FA658302307492E2 CRC64;
MADIQHTQTH PKFTLSDKTR SQKPRDLIQS VKKSAMYHWE NLLPACGIDI PAKDKHGACP
ICGGTDRFHF IDDHHHGNWH CRQCDMPNYG DGLDLVARTK GISITEAAKI VANVLALPLP
ELKPARKTIQ TTQPIADRVA ALMAQTVAGQ SPYLTSKGLH CPNQRLLPDN SAVLRLTTLD
KKVTGAQIIK PDGEKKLLTG SQKKGAFIPL STLEENPNTV IITEGYATAL TVNQFCKGAV
LAALDAGNLL SVAQSVRERW PGTKIIIAAD NDGHHPDELD KNGKPKVNTG KISAEKAAIA
VNGWITLPPT EHKADWDDYR QQYGVETAKL AFAQGLYQPA PITKKAVIQP KDAELSKLTL
CQMGASQRGE VLLARYDGDL ALDSASETVH HYDGIVWCSV SDRDLQREMV AAFMEEKMPY
SPHGIGSAVD ALKLQLPMMN SPERHLIGFR NGVFDLKIGQ FRPHYKHDWL LLANDVEFNS
PVSGETLQNH ATQFWHWLNR ATAHCENKAE RVLAALFMVL ANRCDWQLFL EVTGAGGSGK
SIFAEVCSML AGKGNTVSAS MAALENPRER ALIVGYSLII LPDQTRYVGD GSGIKAITGG
DEVAIDPKHK QPYSTRIPAV VLAVNNNAMS FSDRSGGVSR RRVIFNFSEV VPENERDPLL
RDKIAAELPI IIRQLLHRFA DPQTARRLLA EQQKSEEALD IKRGTDPLVD FCGYLVASHE
ADGLLIGNAE IVPFNPRKYL YHAYLAYMKG NNLNKPVSVT RFGMDMPGAL AEYNQHYLRK
KSKQGIRSNL DLNIDTAIEW LPKLTENNLP EE
//
