ID W1N198_9GAMM Unreviewed; 434 AA.
AC W1N198;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE RecName: Full=L-fuconate dehydratase {ECO:0000256|ARBA:ARBA00013142};
DE EC=4.2.1.68 {ECO:0000256|ARBA:ARBA00013142};
GN ORFNames=BJB45_07655 {ECO:0000313|EMBL:ERL49337.1};
OS Halomonas huangheensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=1178482 {ECO:0000313|EMBL:ERL49337.1, ECO:0000313|Proteomes:UP000019113};
RN [1] {ECO:0000313|EMBL:ERL49337.1, ECO:0000313|Proteomes:UP000019113}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BJGMM-B45 {ECO:0000313|EMBL:ERL49337.1,
RC ECO:0000313|Proteomes:UP000019113};
RA Miao C., Wan Y., Jin W.;
RT "draft genome of Halomonas huanghegensis, strain BJGMM-B45T.";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H2O;
CC Xref=Rhea:RHEA:22772, ChEBI:CHEBI:15377, ChEBI:CHEBI:21291,
CC ChEBI:CHEBI:37448; EC=4.2.1.68;
CC Evidence={ECO:0000256|ARBA:ARBA00001737};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERL49337.1}.
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DR EMBL; AVBC01000055; ERL49337.1; -; Genomic_DNA.
DR RefSeq; WP_021821087.1; NZ_CP013106.1.
DR AlphaFoldDB; W1N198; -.
DR STRING; 1178482.AR456_08950; -.
DR KEGG; hhu:AR456_08950; -.
DR PATRIC; fig|1178482.3.peg.4121; -.
DR eggNOG; COG4948; Bacteria.
DR OrthoDB; 9782675at2; -.
DR Proteomes; UP000019113; Unassembled WGS sequence.
DR GO; GO:0050023; F:L-fuconate dehydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0016052; P:carbohydrate catabolic process; IEA:InterPro.
DR CDD; cd03324; rTSbeta_L-fuconate_dehydratase; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR034610; L-fuconate_dehydratase.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR013341; Mandelate_racemase_N_dom.
DR InterPro; IPR046945; RHMD-like.
DR PANTHER; PTHR13794; ENOLASE SUPERFAMILY, MANDELATE RACEMASE; 1.
DR PANTHER; PTHR13794:SF58; MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF02746; MR_MLE_N; 1.
DR SFLD; SFLDS00001; Enolase; 1.
DR SFLD; SFLDF00111; L-fuconate_dehydratase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019113}.
FT DOMAIN 200..295
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
SQ SEQUENCE 434 AA; 48801 MW; 38A5BD4B5BFDB817 CRC64;
MTIITQVEAR DIRFPTSRQL DGSDAMNEAP DYSAAYVILH TDQSDDLTGH GLTFTIGRGN
DICVAAINAM ASRLEGRHLE DITANMGQFW REMTSGDSQL RWLGPEKGVI HLAASAMINA
VWDLWAKREG KPIWKLLVDM SPEQLVSCLD FRFVTDALTP QEAIAMLKHM APGKEAREAE
MRANGYPAYT TSAGWLGYDE DKVRRLCREA LDDGWEHFKQ KVGGNLEEDR RRAAIIRDEI
GEQRTLMMDA NQVWDVDETI ANMRDLAEFN PHWIEEPTSP DDILGHAEIR NRLFDSGIGV
ATGEHCHNRV MFKQFMQAGA IDYCQLDAAR LGGLNEVIMV LLLAAKFDIP VCPHGGGVGL
CEYTQHVSMF DYIAVSGSLE GRLLEYVDHL HDHFIDPVRI RRGHYLLPEA PGYSITMKAA
SLDDHTYPTG REWQ
//
