ID W1N6N6_9GAMM Unreviewed; 371 AA.
AC W1N6N6;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=CobW {ECO:0000313|EMBL:ERL50610.1};
GN ORFNames=BJB45_05630 {ECO:0000313|EMBL:ERL50610.1};
OS Halomonas huangheensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=1178482 {ECO:0000313|EMBL:ERL50610.1, ECO:0000313|Proteomes:UP000019113};
RN [1] {ECO:0000313|EMBL:ERL50610.1, ECO:0000313|Proteomes:UP000019113}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BJGMM-B45 {ECO:0000313|EMBL:ERL50610.1,
RC ECO:0000313|Proteomes:UP000019113};
RA Miao C., Wan Y., Jin W.;
RT "draft genome of Halomonas huanghegensis, strain BJGMM-B45T.";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERL50610.1}.
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DR EMBL; AVBC01000039; ERL50610.1; -; Genomic_DNA.
DR RefSeq; WP_021820663.1; NZ_CP013106.1.
DR AlphaFoldDB; W1N6N6; -.
DR STRING; 1178482.AR456_06985; -.
DR KEGG; hhu:AR456_06985; -.
DR PATRIC; fig|1178482.3.peg.3705; -.
DR eggNOG; COG0523; Bacteria.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000019113; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR012824; CobW.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02475; CobW; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR PANTHER; PTHR13748:SF70; PROTEIN COBW; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000019113}.
FT DOMAIN 269..360
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 371 AA; 40819 MW; CDA317FBC093E078 CRC64;
MQLNKIPATV VTGFLGSGKT TLLASLLRGV TGKRIAVIVN EFGEQDIDSD LLRSCALDCD
DERPSSEADD GIYELANGCI CCTVEEEFLP VMKKLVARRD DIDHILIETS GLALPKPLVQ
AFNWPEVRQH CTVDAIITLV DGPAVAAGRY AADVERVEAQ RRADESLDHD PSLRELLDDQ
LSAADLVLVS KTDLLEAGER ERVEALIQKR VPDSVKTLFI DQTLAGDSTR LEALMGIGAA
SEEHIDHIDN HHDRHHAEGA HHDHAHDHFD SCVIRLGDVD GEALAGALRQ LLKDQEIYRA
KGFASIPGKA MRQVVQAVGE RLESYFDRLW RQDEVRHTQL VIIGRSLDEA ALRKALSAAQ
IDDVTEIDVS A
//
