ID W1NFZ9_AMBTC Unreviewed; 904 AA.
AC W1NFZ9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN ORFNames=AMTR_s00010p00140120 {ECO:0000313|EMBL:ERM94124.1};
OS Amborella trichopoda.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX NCBI_TaxID=13333 {ECO:0000313|EMBL:ERM94124.1, ECO:0000313|Proteomes:UP000017836};
RN [1] {ECO:0000313|Proteomes:UP000017836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24357323;
RG Amborella Genome Project;
RT "The Amborella genome and the evolution of flowering plants.";
RL Science 342:1241089-1241089(2013).
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; KI397513; ERM94124.1; -; Genomic_DNA.
DR RefSeq; XP_006826887.1; XM_006826824.2.
DR AlphaFoldDB; W1NFZ9; -.
DR EnsemblPlants; ERM94124; ERM94124; AMTR_s00010p00140120.
DR GeneID; 18422312; -.
DR Gramene; ERM94124; ERM94124; AMTR_s00010p00140120.
DR KEGG; atr:18422312; -.
DR eggNOG; KOG1052; Eukaryota.
DR HOGENOM; CLU_007358_0_2_1; -.
DR OrthoDB; 1011589at2759; -.
DR Proteomes; UP000017836; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF433; GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000017836};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..904
FT /note="Glutamate receptor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004806514"
FT TRANSMEM 594..614
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 656..677
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 835..858
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 473..814
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT DISULFID 762..817
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 904 AA; 101866 MW; CFFADD670C34A004 CRC64;
MANDHGRMLK LGATKLFMFA LLLLVCRATR AEPMSNQETV DEIGVILDLG TRVGKEIKTS
MEIAIRDLRD SRNSRVVLMH LRDSHGDPVE AASTALDLIN NQNVRAIVGL QTRNEAAFVD
QVATTAQVPV ISFSRPYPPP AACYLTPTFL IHMANNDSLQ MRGVAAITSS YQWKLVNVIH
DDADSTIVIF PFLNEALMSV GAKIVQRSVL PTKASLHDMI GTLRKELQRL RATQCRVFVV
HITSIDLANL LFVEAKRMGM MENEYVWLIT DPLTALLDSM DSATISLMQG VIGVTTSFCH
ETREFFSRFK QQFLSEYPEE ERANPSIYGL RAYYMIMVLA QSMKSVGAKR ENNSIIPWIQ
YHNETKRAWD LRESLDGPRL IKEITSIVSR GFSGEIRLTN KELHSSIIQI INIVGKGSRG
IGFWSPETGF SRDEMAREGK STSMNTILAP VIFPGGPSTT FPKGWVVTSD GKKMRIGVPK
RKGFKEFVEV KHHQTLNRIE FRGFVIDVFH KVLDILPYEL PYEFIPYDRS YNDLVYEVYQ
NRFDAVVGDV NILANRSRYV EFSHPFSESG ISLLVTVNDG KPHNAWMFMT PFTMGTWLVT
GALFLYTSIV VWSLEHENNL DFGGSLWDQI GTVLWFTFST LFFSHRENIK SSLSRVVIAI
WLFVVLVLRS SYTASLASTF TVNRLELTEI TLESLLRNKS TVGCQRSSFV PQYLEEVLGF
DPVNIKEITT ADELSEALSN GTIAAAYMEV PYIRAFLSQN KCKGFTMAGP TYRVGGLGFA
FTLGSPLTSD VSKAILSIKE SGEMQYLERK WLYSTECSKV TDVNDDDDSL SLDSFWGLFL
ITGGTSTVVL LLFVVNLLHG YRHLENVEDA GGRAKSMWYF MVALSKYWNH RLVALSFIYT
RKSS
//
