ID W1PA42_AMBTC Unreviewed; 381 AA.
AC W1PA42;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=NADH-quinone oxidoreductase subunit D domain-containing protein {ECO:0000259|Pfam:PF00346};
GN ORFNames=AMTR_s00140p00081000 {ECO:0000313|EMBL:ERN04788.1};
OS Amborella trichopoda.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX NCBI_TaxID=13333 {ECO:0000313|EMBL:ERN04788.1, ECO:0000313|Proteomes:UP000017836};
RN [1] {ECO:0000313|Proteomes:UP000017836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24357323;
RG Amborella Genome Project;
RT "The Amborella genome and the evolution of flowering plants.";
RL Science 342:1241089-1241089(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the complex I 49 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00005769}.
CC -!- SIMILARITY: Belongs to the complex I subunit 1 family.
CC {ECO:0000256|ARBA:ARBA00010535}.
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DR EMBL; KI394169; ERN04788.1; -; Genomic_DNA.
DR AlphaFoldDB; W1PA42; -.
DR STRING; 13333.W1PA42; -.
DR EnsemblPlants; ERN04788; ERN04788; AMTR_s00140p00081000.
DR Gramene; ERN04788; ERN04788; AMTR_s00140p00081000.
DR HOGENOM; CLU_015134_9_1_1; -.
DR OMA; LEMHICK; -.
DR Proteomes; UP000017836; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR Gene3D; 1.10.645.10; Cytochrome-c3 Hydrogenase, chain B; 1.
DR InterPro; IPR001135; NADH_Q_OxRdtase_suD.
DR InterPro; IPR001694; NADH_UbQ_OxRdtase_su1/FPO.
DR InterPro; IPR018086; NADH_UbQ_OxRdtase_su1_CS.
DR InterPro; IPR022885; NDH1_su_D/H.
DR InterPro; IPR029014; NiFe-Hase_large.
DR PANTHER; PTHR11993:SF10; NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11993; NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT; 1.
DR Pfam; PF00346; Complex1_49kDa; 1.
DR Pfam; PF00146; NADHdh; 1.
DR SUPFAM; SSF56762; HydB/Nqo4-like; 1.
DR PROSITE; PS00667; COMPLEX1_ND1_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000017836};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 224..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..232
FT /note="NADH-quinone oxidoreductase subunit D"
FT /evidence="ECO:0000259|Pfam:PF00346"
SQ SEQUENCE 381 AA; 43101 MW; 34336E9E3DE355B3 CRC64;
MRMMHNFFRI GGVAADLPHG WIDKCLDFCD YFLPEVAEYQ KLITRNPIFL ERVEGVGFIA
EEEAINWGLS GPMLRASGIP WDLRKVDHYE CYDEFDWEVQ WQKEGDSLAR YLVRISEMIE
SVKIIQQALE GIPGGPYENL EARRFDRVRN IEWNDFEYRF ISKKPSPTFE LSKQELYVRV
EAPKGELGIF LIGDNSVFPW RWKIRPPGLI NLQILPQLVK RMKLADIMTI LGITIGVLVI
VWLEREISAG IQQRIGPEYA GPLGILQAIA DGTKLLFKED LLPSRGDIRL FSIGPSVVVI
SILLSHLVIP FGYRLVLADL SIGVSLWIAI SSIAPIGLLM SGYASNNKYS FSGGLRAAAQ
SISYEIPLTL CVLSISLRAI R
//
