ID   W1PJ36_AMBTC            Unreviewed;      1264 AA.
AC   W1PJ36;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=5-oxoprolinase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=AMTR_s00012p00059980 {ECO:0000313|EMBL:ERN07734.1};
OS   Amborella trichopoda.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX   NCBI_TaxID=13333 {ECO:0000313|EMBL:ERN07734.1, ECO:0000313|Proteomes:UP000017836};
RN   [1] {ECO:0000313|Proteomes:UP000017836}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24357323;
RG   Amborella Genome Project;
RT   "The Amborella genome and the evolution of flowering plants.";
RL   Science 342:1241089-1241089(2013).
CC   -!- SIMILARITY: Belongs to the oxoprolinase family.
CC       {ECO:0000256|ARBA:ARBA00010403}.
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DR   EMBL; KI393609; ERN07734.1; -; Genomic_DNA.
DR   RefSeq; XP_006846059.1; XM_006845996.2.
DR   AlphaFoldDB; W1PJ36; -.
DR   STRING; 13333.W1PJ36; -.
DR   EnsemblPlants; ERN07734; ERN07734; AMTR_s00012p00059980.
DR   GeneID; 18435963; -.
DR   Gramene; ERN07734; ERN07734; AMTR_s00012p00059980.
DR   KEGG; atr:18435963; -.
DR   eggNOG; KOG1939; Eukaryota.
DR   HOGENOM; CLU_002157_0_1_1; -.
DR   OMA; TDCNVML; -.
DR   OrthoDB; 674at2759; -.
DR   Proteomes; UP000017836; Unassembled WGS sequence.
DR   GO; GO:0017168; F:5-oxoprolinase (ATP-hydrolyzing) activity; IBA:GO_Central.
DR   GO; GO:0006749; P:glutathione metabolic process; IBA:GO_Central.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000017836}.
FT   DOMAIN          10..216
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          236..536
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          560..710
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
FT   DOMAIN          735..1263
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
SQ   SEQUENCE   1264 AA;  137298 MW;  EFD87557BE3CB0A0 CRC64;
     MGSVKGEKFR FCIDRGGTFT DIYAEVPGEP AFRVMKLLSV DPSNYDDAPI EGIRRILEGC
     TGEKIPRSSK IPTDKIEWIR MGTTVATNAL LERKGERIAL CVTKGFEDLL KIGNQARPNI
     FDLKVSMPST LYEEVVEADE RIELVLDGEE EANNQSFVKG ISSELIRISK PLDEEALRPL
     LKGLLAKGIG CLAVVLMHSY TYPQHELAVE RLARSMGFKH VSLSSKLTPM VRAVPRGLTA
     TVDAYLTPVI KEYLSGFMSR FDEKGSDGVN VLFMQSDGGL APERRFSGHK AVLSGPAGGV
     VGYSQTLFGL ETEKALIGFD MGGTSTDVSR YAGTYEQVLE TQIAGAIIQA PQLDINTVAA
     GGGSKLKFQF GAFRVGPESV GAHPGPVCYR KGGELAVTDA NLVLSTVIPD YFPSIFGPNE
     NEPLDIEATR EEFRKLSVVI NSHRKSQDPL AKDMSIEEIA LGFIDVANET MCRPIRQLTE
     MKGHETRNHA LGCFGGAGPQ HACAIARSLG MTEVLIHRYC GILSAYGMGL ADVIEEAQEP
     YSAVYGEESV SEASRREAIL SEQVKLKLRD QGFGDGSITT ESYLNLRYEG TDTAIMVKKP
     EKGGSSYAEE FVKLFQREYG FKLQNRQILI CDVRVRGVGV TNILKPQLVN RVFEAPKAEK
     CYKVYFGGGW KETPLFKLEN LGYGHVIDGP AVIMNGNSTV IVEPGCKANI TKYGNIRIEI
     SSVPNTISLS EKVADVVQLS IFNHRFMGIA EQMGRTLQRT SISTNIKERL DFSCALFCPN
     GGLVANAPHV PVHLGAMSST VSWQLKYWGD NLKEGDVLVT NHPSAGGSHL PDITVITPVF
     DMGKLVFFVA SRGHHAEIGG ITPGSMPPFS KAIWEEGASI KAFKLVENGI FQEEGIIKLL
     ESSSIDGKVG VPGTRRLQDN LSDLRAQVAA NQRGIGLIKE LIEQYGLAHV QAYMGHVQTN
     AESTVREMLR SVAAKVSKQT NIGNSGDSVL LEEEDYMDDG SIIHLKLSID GKKGEAVFDF
     DGTSHEVYGN WNAPEAVTAA AVIYSLRCLV DVDIPLNQGC LAPVIIKIPP GSFLSPSDKA
     AVVGGNVLTS QRITDVILTA FQACACSQGC MNNLTFGDDT FGYYETIGGG CGAGPSWNGT
     SGVQCHMTNT RMTDPEIFEQ RYPVLLHRFG LREKSGGAGK FKGGEGLVRD IEFRRPVVVS
     MLSERRVHAP RGLMGGKNGG RGANFLIRRD KRRVYLGGKN TIEVEPGEVL QILTPGGGGW
     GCPE
//