ID W1PLZ7_AMBTC Unreviewed; 1150 AA.
AC W1PLZ7;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=AMTR_s00024p00109280 {ECO:0000313|EMBL:ERN11057.1};
OS Amborella trichopoda.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX NCBI_TaxID=13333 {ECO:0000313|EMBL:ERN11057.1, ECO:0000313|Proteomes:UP000017836};
RN [1] {ECO:0000313|Proteomes:UP000017836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24357323;
RG Amborella Genome Project;
RT "The Amborella genome and the evolution of flowering plants.";
RL Science 342:1241089-1241089(2013).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR EMBL; KI392710; ERN11057.1; -; Genomic_DNA.
DR AlphaFoldDB; W1PLZ7; -.
DR EnsemblPlants; ERN11057; ERN11057; AMTR_s00024p00109280.
DR Gramene; ERN11057; ERN11057; AMTR_s00024p00109280.
DR eggNOG; ENOG502QS1K; Eukaryota.
DR HOGENOM; CLU_000288_22_4_1; -.
DR OMA; CSNVEWI; -.
DR Proteomes; UP000017836; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR GO; GO:0009755; P:hormone-mediated signaling pathway; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1490.310; -; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR045381; BRI1_island_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48056; LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED; 1.
DR PANTHER; PTHR48056:SF14; NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE; 1.
DR Pfam; PF20141; Island; 1.
DR Pfam; PF00560; LRR_1; 11.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00369; LRR_TYP; 8.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000017836};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 755..778
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 841..1150
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 937..976
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 870
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1150 AA; 125171 MW; E6F0A0C6A66BE503 CRC64;
MISTLSSSMD LDGKLRALVV LIFFLVLLPS VRHVDSSDGE KTDFEALLMF KKAVEKDKKG
ILHGWVPNKG QCNWYGVSCT SQRVTKLDLS QAELSGSLPL TTLASMDSLL VLNLSFNSFF
LNASSLVQLP PSLQYLDLSF NGIFGSVPEG LFLNNPNLIS LQLPHNNLSG SLPENLLAKG
ISDNLQFLDL SYNNISGPIW SENSCNALLY LDLSKNTLSG EIPSSLSDCY NLNTLNLSFN
GLSGGIPVSF KGFTKLQSLD LSQNHLNGII PQELANSCET LQQLRLSSNN ISGSFPLSFS
PCSSLKLLDL SNNNISGPFD DSIAGNLQAL ETLLMSNNFV SGEIPASISN CKNLKVMDFS
SNKLSGHIPE NLCPGLALLE ELRLPDNLLS GGIPPSLAQC PNLKTIDLSI NYLNGTIPPE
FGGLKNLEHF MAWFNGLSGP LPKELGHCSN LKTLILNNNL LSGQMPPEIF NSSNLEWISL
TSNGISGQIS PEFGQLKRLA ILQLANNSFS GVIPKELGNC SSLVWLDLNS NQLSGVIPAY
LGRKPNEKPL SGILSGNTLA FVRNVGNSCK GVGGLLEFAG IRPERLLQVP TLKTCDFTRL
YSGAALNDWT HYQSLEYLDL SYNNLNGSIP EEFGSMIVLQ VLGLSHNKIT GEIPSSLGNL
RYLGVFDASH NHLQGRIPES FSNLTFLVQI DLSDNALTGP IPSRGQLSTL PASQYRDNPG
LCGVPLAPCQ SDNPSLNGSG NYSAEVPVKP RPATWANSMV LGILVSMATT CVLIVWAVTV
RGRRRAAAAA KAAMINSLQA SYATTWKIGK EKEPLSINVA TFQRPLRKLT FSQLIEATNG
FCAGSLIGSG GFGEVFKATL KDGSSVAIKK LIRLSCQGDR EFMAEMETLG KIKHRNLVPL
LGYCKIGEER LLVYEYMEFG SLEEMLHGDR NKLFGDKAST SGEKKEIPGN EKMGFHGDKK
ENSGNEKMGF HGENKENAGN EKMAFYNDKK EKPLMAFSSE KTGFSIEKPT VTGGFLSWEL
RKKIAKGAAK GLAFLHHNCI PHIIHRDMKS SNVLLDSFME ARVSDFGMAR LISCLDTHLS
VSTLAGTPGY VPPEYYQSFR CTAKGDVYSF GVVMLEILTG KRPTDKEEFG ETNLVGWVKA
HVRDKAGEWR
//
