ID W1PVX9_AMBTC Unreviewed; 1340 AA.
AC W1PVX9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=AMTR_s00022p00074370 {ECO:0000313|EMBL:ERN11455.1};
OS Amborella trichopoda.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX NCBI_TaxID=13333 {ECO:0000313|EMBL:ERN11455.1, ECO:0000313|Proteomes:UP000017836};
RN [1] {ECO:0000313|Proteomes:UP000017836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24357323;
RG Amborella Genome Project;
RT "The Amborella genome and the evolution of flowering plants.";
RL Science 342:1241089-1241089(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC PRP16 sub-subfamily. {ECO:0000256|ARBA:ARBA00038040}.
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DR EMBL; KI392687; ERN11455.1; -; Genomic_DNA.
DR RefSeq; XP_006849874.1; XM_006849811.2.
DR STRING; 13333.W1PVX9; -.
DR EnsemblPlants; ERN11455; ERN11455; AMTR_s00022p00074370.
DR GeneID; 18439651; -.
DR Gramene; ERN11455; ERN11455; AMTR_s00022p00074370.
DR KEGG; atr:18439651; -.
DR eggNOG; KOG0924; Eukaryota.
DR HOGENOM; CLU_001832_6_5_1; -.
DR OMA; VDVMFHR; -.
DR OrthoDB; 5488182at2759; -.
DR Proteomes; UP000017836; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF91; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000017836}.
FT DOMAIN 652..815
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 829..1017
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 73..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1271..1340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..141
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..304
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 356..379
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..410
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1271..1320
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1340 AA; 151431 MW; 47B919DC88DBE1D1 CRC64;
MEGIAGLDET KDVLEPDKGS KGGLYVPGKD RVIFRPPPER KSILGLDALA IAKGGRKSEH
GFKVPMDRIV SSMASLDAEE KSDFQESEDG SSDVPQREHE LAHRHYRESS SREKLSLEKE
REAASETQSS SERHRTKDCT PSSDISRSSP YRTPRRHGME GYGSGRRESE AEERSDSKKQ
RYDSDGDKDY RGRESHRRHD GYDQMYVGEH GRKRSRDAYS SRSSGAEERS DSKKQRYDSD
GDKDYRGRES HRRHDGYDQM YAGEHGRKRS RDAYSSRSSS KSDWDDGGWE WEDTPRRDSP
HVPSRNHLPA HSPMLAGASP DARLVSPWLG GHTPYTSVSA SPWDSVTPSP APIHASGVPT
RSSMSRGQRS HQLSFPSEKS QPRFEDDGVH KRSLSKEESQ DVTERMRVEI EDAERDADRA
WYDREESGAI FDADSSSIFL GDEATFQKKE TELAKRLIRK DGTRMSLSQS KKLSQLTADN
AQWEDRQLLR SGAVRGTEVQ TEFEDEDEKK VILLVHDTKP PFLDGRVVFT KQAEPIMPVK
DPTSDMAIIS RKGSALVREI HEKQSMNKSR QRFWELAGSA LGNILGVEKS AEQIDADTAE
VGEHGEVDFK EDAKFASHMK EKGEAVSDFA KTKSLMEQRQ YLPIYSVREE LLQVVRENQV
IVVVGETGSG KTTQLTQYLH EDGFTQGGII GCTQPRRVAA MSVAKRVSEE METELGDKVG
YAIRFEDVTG KNTVIKYMTD GVLLRETLRE PDLETYRVVV MDEAHERSLS TDVLFGILKQ
VVSRRRDFKL IVTSATLNAQ KFSNFFGSVP IFHIPGRTFP VNILYSKTPC EDYIEAAVKQ
AMTIHITSPP GDILIFMTGQ DEIEATCYAL AERMEQLVST TKKGISNLSI LPIYSQLPAD
LQAKIFQKAE GGARKCIVAT NIAETSLTVD GILYVIDTGY GKMKVYNPRM GMDALQVFPA
SRAAADQRAG RAGRTGPGTC YRLYTETAYQ NEMLPNPVPE IQRTNLGNVV LLLKSLNVEN
LLDFDFMDPP PQDNILNSMY QLWVLGALDN VGRLTDLGRK MVEFPLDPPL AKMLLIGEKL
RCVNEVLTIV SMLSVPSVFF RPKDRAEESD AAREKFFVPE SDHLTLLHVY QQWKANNYRG
DWCNDHFLHV KGLRKAREVR SQLLDILKMQ KIELTSCGPD WDVVRKAICS AYFHNAARLK
GVGEYVNCRT GMPCHLHPSS SLYGLGYTPD YVVYHELVLT TKEYMQCVTS VEPQWLAELG
PMFFSVKDSD TSMLEHKKRQ KEEKSAMEEE MEELRRVRAQ EERENKEREK EKREKEKQMI
AMPGAKPPSG KIRPRGRLGL
//
