ID W1QBF6_OGAPD Unreviewed; 561 AA.
AC W1QBF6;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Flavoprotein domain-containing protein {ECO:0000259|Pfam:PF02441};
GN ORFNames=HPODL_01163 {ECO:0000313|EMBL:ESW97052.1};
OS Ogataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL
OS Y-7560 / DL-1) (Yeast) (Hansenula polymorpha).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Ogataea.
OX NCBI_TaxID=871575 {ECO:0000313|EMBL:ESW97052.1, ECO:0000313|Proteomes:UP000008673};
RN [1] {ECO:0000313|EMBL:ESW97052.1, ECO:0000313|Proteomes:UP000008673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1
RC {ECO:0000313|Proteomes:UP000008673};
RX PubMed=24279325; DOI=10.1186/1471-2164-14-837;
RA Ravin N.V., Eldarov M.A., Kadnikov V.V., Beletsky A.V., Schneider J.,
RA Mardanova E.S., Smekalova E.M., Zvereva M.I., Dontsova O.A., Mardanov A.V.,
RA Skryabin K.G.;
RT "Genome sequence and analysis of methylotrophic yeast Hansenula polymorpha
RT DL1.";
RL BMC Genomics 14:837-837(2013).
RN [2] {ECO:0000313|Proteomes:UP000008673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1
RC {ECO:0000313|Proteomes:UP000008673};
RA Ravin N.V., Mardanov A.V., Eldarov M.A., Kadnikov V.V., Beletsky A.V.,
RA Zvereva M.I., Smekalova E.M., Dontsova O.A., Skryabin K.G.;
RT "Genome sequence of the methylotrophic yeast Hansenula polymorpha DL1.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HFCD (homooligomeric flavin containing Cys
CC decarboxylase) superfamily. {ECO:0000256|ARBA:ARBA00038350}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESW97052.1}.
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DR EMBL; AEOI02000009; ESW97052.1; -; Genomic_DNA.
DR RefSeq; XP_013933137.1; XM_014077662.1.
DR AlphaFoldDB; W1QBF6; -.
DR STRING; 871575.W1QBF6; -.
DR GeneID; 25770627; -.
DR KEGG; opa:HPODL_01163; -.
DR eggNOG; KOG0672; Eukaryota.
DR HOGENOM; CLU_014402_2_0_1; -.
DR OrthoDB; 168599at2759; -.
DR Proteomes; UP000008673; Chromosome VI.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1950; Flavin prenyltransferase-like; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR036551; Flavin_trans-like.
DR InterPro; IPR003382; Flavoprotein.
DR PANTHER; PTHR14359; HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY; 1.
DR PANTHER; PTHR14359:SF6; PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE; 1.
DR Pfam; PF02441; Flavoprotein; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF52507; Homo-oligomeric flavin-containing Cys decarboxylases, HFCD; 1.
PE 3: Inferred from homology;
KW Coenzyme A biosynthesis {ECO:0000256|ARBA:ARBA00022993};
KW Reference proteome {ECO:0000313|Proteomes:UP000008673}.
FT DOMAIN 314..493
FT /note="Flavoprotein"
FT /evidence="ECO:0000259|Pfam:PF02441"
FT REGION 1..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 199..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 507..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 214..293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 514..551
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 561 AA; 61388 MW; 5F5294D8646E5DE0 CRC64;
MSLSEKSINT VGTDSKTKSE THLEKPSTGK GTISNKVSQQ QQPMPRPILF KSGSSASSIV
SKQSNLPPLN TTFDKAQKNT QPISQPTPLG DSVPYTPSTQ AHTSGDLTSE SSTPMKSASS
ISFQVPTVNP QKHRGSISAR PSTTKLSLLE SPASGVPSSR QPSGTHPPTA LGHEFPHQVK
HTDVGSSKTT PTTAVPLHSA LGKESREHSV SSIFSDRHPS SHSSPRNLSS PSGVTSPVSF
DLGPQSSQNS TVGADTLRNE ILFQPLSNEN RVQSPPMASR KKTTTTPKTV VSTPTGPVVP
FTEYLSKEDD DKIHILIGAT GSVATIKIPM IIDKLFKLYG VDKVSIQLVV TQAAEHFLHG
LKISTEVKIW RENEEWSTPM TKPGDPILHV ELRKWADIFL IAPLSANTLA KIANGIADNL
LTSIIRVWNP AIPIIMAPAM NTLMYTHPIT KKHFAVIKED FKFVEVLKPI EKVLICGDIG
MGGMREWSEI VDILYRKMKT LQAEKLKKAN ERIEEEEEEE EEEEDDDEDD EDDDDDFDDD
FDDDEDDDVE STVIESKSSR G
//
