ID W1QFY5_OGAPD Unreviewed; 973 AA.
AC W1QFY5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Hydantoin utilization protein A {ECO:0008006|Google:ProtNLM};
GN ORFNames=HPODL_03758 {ECO:0000313|EMBL:ESW99891.1};
OS Ogataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL
OS Y-7560 / DL-1) (Yeast) (Hansenula polymorpha).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Ogataea.
OX NCBI_TaxID=871575 {ECO:0000313|EMBL:ESW99891.1, ECO:0000313|Proteomes:UP000008673};
RN [1] {ECO:0000313|EMBL:ESW99891.1, ECO:0000313|Proteomes:UP000008673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1
RC {ECO:0000313|Proteomes:UP000008673};
RX PubMed=24279325; DOI=10.1186/1471-2164-14-837;
RA Ravin N.V., Eldarov M.A., Kadnikov V.V., Beletsky A.V., Schneider J.,
RA Mardanova E.S., Smekalova E.M., Zvereva M.I., Dontsova O.A., Mardanov A.V.,
RA Skryabin K.G.;
RT "Genome sequence and analysis of methylotrophic yeast Hansenula polymorpha
RT DL1.";
RL BMC Genomics 14:837-837(2013).
RN [2] {ECO:0000313|Proteomes:UP000008673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1
RC {ECO:0000313|Proteomes:UP000008673};
RA Ravin N.V., Mardanov A.V., Eldarov M.A., Kadnikov V.V., Beletsky A.V.,
RA Zvereva M.I., Smekalova E.M., Dontsova O.A., Skryabin K.G.;
RT "Genome sequence of the methylotrophic yeast Hansenula polymorpha DL1.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESW99891.1}.
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DR EMBL; AEOI02000007; ESW99891.1; -; Genomic_DNA.
DR RefSeq; XP_013935563.1; XM_014080088.1.
DR AlphaFoldDB; W1QFY5; -.
DR STRING; 871575.W1QFY5; -.
DR GeneID; 25773192; -.
DR KEGG; opa:HPODL_03758; -.
DR eggNOG; ENOG502QQBE; Eukaryota.
DR HOGENOM; CLU_007154_0_0_1; -.
DR OMA; IDMMKTS; -.
DR OrthoDB; 307246at2759; -.
DR Proteomes; UP000008673; Chromosome IV.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 2.40.390.10; CV3147-like; 1.
DR Gene3D; 3.40.1610.10; CV3147-like domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR048350; DUF917_C.
DR InterPro; IPR024071; DUF917_C_sf.
DR InterPro; IPR010318; DUF917_N.
DR InterPro; IPR027479; DUF917_N_sf.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR PANTHER; PTHR11365:SF10; HYDANTOINASE; 1.
DR Pfam; PF06032; DUF917; 1.
DR Pfam; PF20906; DUF917_C; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF160991; CV3147-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008673}.
FT DOMAIN 3..181
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 201..381
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 592..756
FT /note="DUF917"
FT /evidence="ECO:0000259|Pfam:PF06032"
FT DOMAIN 760..958
FT /note="DUF917"
FT /evidence="ECO:0000259|Pfam:PF20906"
SQ SEQUENCE 973 AA; 105049 MW; C4A6DF19FE7910A2 CRC64;
MLIGVDVGGT NTDSVLIDPT KINTDSHGVL AWNKMVTSAE VSDSIQKGIS KLFVDHKNVD
KKDVASVTIG TTHFINAVVE QDRARLDKVA VLRLCGPYSR HVYPFSDFPS GLTAVIKGYI
GYLNGGFHVD GNEIQPVKKE EVLEHVRKAK ELGITSFAVI GIFSHMKPEQ EELVKEIILE
EIPHAKVSVS HQVSGIGFLE RENATILNAS ILHFAEKIIS SFANAIKKLG LSCPVFLTQN
DGTILSAAEA LSLPIRTFSS GATNSMRGAS FLAKTHGKSA IVLDVGGTTT DVGLLLSTGF
PRQSSSYSIV GGVKMNFSMP HVESIGLGGG SLVRGAGDAL TIGPDSTGSE IVKRALVFGG
SDVTATDCAV AAELLQGGSL EIGTVSHVKD KFSPEYLAAF QKRAKVMVEK AIDRMKTSPD
DITVLAVGGG SFIVPEHLDG ASAVIRPPFY SVANAIGAAM GKVSVEISEI KLLAPGTTSK
EEVLEKLRKK AIEKILAKGG LEDTIETVFV STDAIPYVPN TFEFVIKIVA DVDYSKAPKL
EVDEGQFESG TRDIVKKSLY EETNTAVEEE IDYTTYRPTI NKDRQWVLSE VDLDFLAIGA
YILGCGGGGN PYSYMLEVRN YLRQGDTVTV VDLEDAHRYI KGEGSIVGVC YAGSPTVSHE
QMLGEALMES YDIMAKYINR KPELLFPIEI GGGNGLCTFQ ISASSRLNLP VVDCDTMGRA
YPTHWQTTPV VCTPEGECFY APMVFANGNG NSVIMASSKS DLLLEKTMRA SLAELGSKVG
VVNPPMSLKD VEEKNIHGSI SLAWRIGRAV KIARQKAEID KLPQRILESV NNTGKLLFSG
KIVDVERKLF KGHAWGEVVI EEVDGARRKM TIPFKNENIY CKTTDADGTN EEIVCSVPDL
IAVVDAATGE AVGTSDYRYG LLVFVLGIAP SNKWTDTERG VRIGGPAGFD LDFEYKPIST
YSKPMSVIQE YAY
//
