ID W1UIP0_9STRE Unreviewed; 328 AA.
AC W1UIP0;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=HTH-type transcriptional regulator MalR {ECO:0000313|EMBL:ETI93627.1};
GN ORFNames=Q617_SPSC00320G0003 {ECO:0000313|EMBL:ETI93627.1};
OS Streptococcus sp. DORA_10.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1403937 {ECO:0000313|EMBL:ETI93627.1, ECO:0000313|Proteomes:UP000018865};
RN [1] {ECO:0000313|EMBL:ETI93627.1, ECO:0000313|Proteomes:UP000018865}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DORA_10 {ECO:0000313|Proteomes:UP000018865};
RA Brown C.T., Sharon I., Thomas B.C., Castelle C.J., Morowitz M.J.,
RA Banfield J.F.;
RT "A Varibaculum cambriense genome reconstructed from a premature infant gut
RT community with otherwise low bacterial novelty that shifts toward anaerobic
RT metabolism during the third week of life.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETI93627.1}.
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DR EMBL; AZMH01000320; ETI93627.1; -; Genomic_DNA.
DR AlphaFoldDB; W1UIP0; -.
DR PATRIC; fig|1403937.3.peg.1053; -.
DR Proteomes; UP000018865; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06294; PBP1_MalR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR001761; Peripla_BP/Lac1_sug-bd_dom.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF00532; Peripla_BP_1; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..57
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT DOMAIN 4..47
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 328 AA; 36790 MW; 4B9E9F3F7D48F8F3 CRC64;
MPVTIKDVAK AAGVSPSTVT RVIQNKSTIS DETKKRVRKA MKELNYHPNL NARSLVSSYT
QVIGLVLPDD SDAFYQNPFF PSVLRGIAQV ASENHYAIQI ATGKDEKERL KAISQMVYGK
RVDGLIFLYA EEEDPLVKLV ADEQFPFLIL GKSISPFIPL VDNDNVQAGF DATEYFIKKG
CKRIAFIGGT KRLFVTQDRL TGYESALKQY QLPIDGNLTY FATEFLEEKG YQFSKLLFQH
DPQIDAIITT DSLLAEGVCD YIAKHQLDVP VLSFDSVNPK LNLAAYVDIN SLELGRVSLE
TILQIINDAK SNKQICYRQL IAHKIIEK
//
