ID W2BWY3_9FIRM Unreviewed; 419 AA.
AC W2BWY3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Group II intron reverse transcriptase/maturase {ECO:0000313|EMBL:ETJ99327.1};
DE EC=2.7.7.49 {ECO:0000313|EMBL:ETJ99327.1};
GN Name=ltrA_3 {ECO:0000313|EMBL:ETJ99327.1};
GN ORFNames=HMPREF0378_0132 {ECO:0000313|EMBL:ETJ99327.1};
OS Eubacterium nodatum ATCC 33099.
OC Bacteria; Bacillota; Clostridia; Eubacteriales;
OC Eubacteriales Family XIII. Incertae Sedis.
OX NCBI_TaxID=1161902 {ECO:0000313|EMBL:ETJ99327.1, ECO:0000313|Proteomes:UP000018868};
RN [1] {ECO:0000313|EMBL:ETJ99327.1, ECO:0000313|Proteomes:UP000018868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33099 {ECO:0000313|EMBL:ETJ99327.1,
RC ECO:0000313|Proteomes:UP000018868};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETJ99327.1}.
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DR EMBL; AZKM01000022; ETJ99327.1; -; Genomic_DNA.
DR AlphaFoldDB; W2BWY3; -.
DR STRING; 1161902.HMPREF0378_0132; -.
DR PATRIC; fig|1161902.3.peg.1215; -.
DR eggNOG; COG3344; Bacteria.
DR OrthoDB; 9788687at2; -.
DR Proteomes; UP000018868; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01651; RT_G2_intron; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR030931; Group_II_RT_mat.
DR InterPro; IPR013597; Mat_intron_G2.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR NCBIfam; TIGR04416; group_II_RT_mat; 1.
DR PANTHER; PTHR34047:SF2; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR34047; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF08388; GIIM; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleotidyltransferase {ECO:0000313|EMBL:ETJ99327.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018868};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:ETJ99327.1};
KW Transferase {ECO:0000313|EMBL:ETJ99327.1}.
FT DOMAIN 49..275
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 419 AA; 48755 MW; 4FEC24207078C5A6 CRC64;
MSQLLEEILS RNNMMLAYKR VVANKGAGGV DGISTEDVKQ HLTENWEKIR EQIRNRKYKP
SPVRRVEIPK PNGGVRNLGI PTVVDRIIEQ AIAQRLTPMC EPLFSENSYG FRPKRRAQQA
VIKLLEYLND GHMYIVDIDL EKFFDNVNHD KLMYLVHEII NDGDTESLIQ KYLNAGVMVQ
GEYERTEKGT PQGGNISPLL SNIMLNELDR ELEERGLHFV RYADDCVIAV GSSAAANRVM
HTVTKWIEKK LGLKVNMTKT KVTKPSRLKY LGFGFWKDSK DSMWKARPHK DSVERFKRKL
KRLTKRSWSI TMDERIEKLN QAIRGWINYY RIGSMKTALR TIDEHLRTRM RIVIWKQWKT
REKRMWGLRK LGAPEWMAKQ SAGCCDHYQV VAKTGGLRLI NKEILARRGL LSCLDYYLN
//
