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Database: UniProt
Entry: W2C0U5_9FIRM
LinkDB: W2C0U5_9FIRM
Original site: W2C0U5_9FIRM 
ID   W2C0U5_9FIRM            Unreviewed;       132 AA.
AC   W2C0U5;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   10-APR-2019, entry version 24.
DE   RecName: Full=Mini-ribonuclease 3 {ECO:0000256|HAMAP-Rule:MF_01468};
DE            Short=Mini-3 {ECO:0000256|HAMAP-Rule:MF_01468};
DE            Short=Mini-RNase 3 {ECO:0000256|HAMAP-Rule:MF_01468};
DE            EC=3.1.26.- {ECO:0000256|HAMAP-Rule:MF_01468};
DE   AltName: Full=Mini-RNase III {ECO:0000256|HAMAP-Rule:MF_01468};
DE            Short=Mini-III {ECO:0000256|HAMAP-Rule:MF_01468};
GN   Name=mrnC {ECO:0000256|HAMAP-Rule:MF_01468};
GN   ORFNames=HMPREF0378_1587 {ECO:0000313|EMBL:ETK00071.1};
OS   Eubacterium nodatum ATCC 33099.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales;
OC   Clostridiales Family XIII. Incertae Sedis.
OX   NCBI_TaxID=1161902 {ECO:0000313|EMBL:ETK00071.1, ECO:0000313|Proteomes:UP000018868};
RN   [1] {ECO:0000313|EMBL:ETK00071.1, ECO:0000313|Proteomes:UP000018868}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33099 {ECO:0000313|EMBL:ETK00071.1,
RC   ECO:0000313|Proteomes:UP000018868};
RA   Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M.,
RA   Haft D.H., Methe B., Sutton G., Nelson K.E.;
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in correct processing of both the 5' and 3'
CC       ends of 23S rRNA precursor. Processes 30S rRNA precursor
CC       transcript even in absence of ribonuclease 3 (Rnc); Rnc processes
CC       30S rRNA into smaller rRNA precursors. {ECO:0000256|HAMAP-
CC       Rule:MF_01468}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_01468};
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01468}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01468}.
CC   -!- SIMILARITY: Belongs to the MrnC RNase family. {ECO:0000256|HAMAP-
CC       Rule:MF_01468}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ETK00071.1}.
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DR   EMBL; AZKM01000008; ETK00071.1; -; Genomic_DNA.
DR   RefSeq; WP_034819290.1; NZ_AZKM01000008.1.
DR   STRING; 1161902.HMPREF0378_1587; -.
DR   EnsemblBacteria; ETK00071; ETK00071; HMPREF0378_1587.
DR   PATRIC; fig|1161902.3.peg.455; -.
DR   OrthoDB; 1939897at2; -.
DR   BioCyc; GCF_000510425-HMP:HMPREF0378_RS02215-MONOMER; -.
DR   Proteomes; UP000018868; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR   CDD; cd00593; RIBOc; 1.
DR   Gene3D; 1.10.1520.10; -; 1.
DR   HAMAP; MF_01468; RNase_Mini_III; 1.
DR   InterPro; IPR008226; Mini3_fam.
DR   InterPro; IPR000999; RNase_III_dom.
DR   InterPro; IPR036389; RNase_III_sf.
DR   Pfam; PF00636; Ribonuclease_3; 1.
DR   PIRSF; PIRSF005520; UCP005520; 1.
DR   SMART; SM00535; RIBOc; 1.
DR   SUPFAM; SSF69065; SSF69065; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000018868};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01468};
KW   Endonuclease {ECO:0000256|HAMAP-Rule:MF_01468};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01468};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_01468};
KW   Nuclease {ECO:0000256|HAMAP-Rule:MF_01468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018868};
KW   Ribosome biogenesis {ECO:0000256|HAMAP-Rule:MF_01468};
KW   RNA-binding {ECO:0000256|HAMAP-Rule:MF_01468};
KW   rRNA processing {ECO:0000256|HAMAP-Rule:MF_01468};
KW   rRNA-binding {ECO:0000256|HAMAP-Rule:MF_01468}.
FT   DOMAIN        3    128       RNase III. {ECO:0000259|SMART:SM00535}.
FT   ACT_SITE     18     18       {ECO:0000256|HAMAP-Rule:MF_01468}.
SQ   SEQUENCE   132 AA;  14801 MW;  5E3BF903E0215920 CRC64;
     MEVNAKTANT TALAYIGDAV YEVYIRKYVL GDAPAGVNRM NRRVIRYVCA DGQAKIAKEL
     VKGFLSEDEI KLLKRGRNNT KTPKPRGSSP VDYKMATGFE ALIGYLHLNG NVKRLEEIIR
     ESIEIIEREG NL
//
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