ID W2EIX5_9ACTN Unreviewed; 952 AA.
AC W2EIX5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 13-SEP-2023, entry version 44.
DE RecName: Full=OmpR/PhoB-type domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=MPTA5024_37760 {ECO:0000313|EMBL:ETK30921.1};
OS Microbispora sp. ATCC PTA-5024.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Microbispora.
OX NCBI_TaxID=316330 {ECO:0000313|EMBL:ETK30921.1, ECO:0000313|Proteomes:UP000018869};
RN [1] {ECO:0000313|EMBL:ETK30921.1, ECO:0000313|Proteomes:UP000018869}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC PTA-5024 {ECO:0000313|EMBL:ETK30921.1,
RC ECO:0000313|Proteomes:UP000018869};
RX PubMed=24459268;
RA Sosio M., Gallo G., Pozzi R., Serina S., Monciardini P., Bera A.,
RA Stegmann E., Weber T.;
RT "Draft Genome Sequence of the Microbispora sp. Strain ATCC-PTA-5024,
RT Producing the Lantibiotic NAI-107.";
RL Genome Announc. 2:e01198-13(2014).
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETK30921.1}.
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DR EMBL; AWEV01000302; ETK30921.1; -; Genomic_DNA.
DR AlphaFoldDB; W2EIX5; -.
DR HOGENOM; CLU_004665_1_3_11; -.
DR OrthoDB; 3194665at2; -.
DR Proteomes; UP000018869; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001126; UmuC.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000018869}.
FT DOMAIN 1..96
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DOMAIN 267..337
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT DNA_BIND 1..96
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT NON_TER 952
FT /evidence="ECO:0000313|EMBL:ETK30921.1"
SQ SEQUENCE 952 AA; 101633 MW; 5F86F36249A2E4A0 CRC64;
MRFGVLGPVD VTTDAGEPVT VPGVKVRALL ADLLANRNQV VSADRLIEDL WGDAPPANPA
GALQVRVSQL RKALNDAEPG ARDLVESRPP GYLLRATADA DRFAELTAAG DADRLTEALA
LWRGEPYADF ADEEYVRAEA VRLAEQRLVV LERLAELRLA RGEHDLAAAD LADLVTRHPL
RESLRALHLR ALYAAGRQTE ALESYAGLRE RLAEEMGVDP GPDLVALHGR ILAQDAGLTG
PPRTALIRNS LPARLDELVG RAEALTELRA LIPEHRLVTL TGPGGVGKTR LATEAAREQA
YPDGVHVVEL AALPPGDPGV AERVLTALDV REVAGAGVPA AERLLAAVGR RRLLLVLDNC
EHVVEPAAGL VARLLRDAPG VTVLATSREP LGLTGELVWE VPPLALPDEE RDLDAVRRSA
AARLFAARAA ARQRGFRLDE RTAPAVARIC RRLDGLPLAL ELAATRVRAL GVAGVAERLD
DRFTLLATTQ RDLPERQRTL AAAIGWSWDL LDDADREVLA RLAVFGGGCA PDAAEAVCGA
GLDVLARLVD RSLVVLDDTA AGPRHRLLES VAAFCLDRLE TVRPGGVAEA RARHAAYYTE
LAERADPELR GPAQAEWLSR LDAEDGNLRA ALAHGGGLRL ANALTWYWFL RGRFTEARRA
LALDGDASHR AGAEAWRAGF ALLQGDEADT AGVSAYDDGR GTWFVAAALI ERGELTLAEE
LLSSAEDAAG KAADRWTEAA VLASRAKLAH AGGDLAALER DGARSAEIFA ELGDRWGGVQ
AGQWMAGLAE LTGDHDRAAA LLREALSRAE ELSLWPEVGT ALSWLAWLAV QTRDYGRARE
LAGRAYRLAA EQDWPAAMVF AELGLGFAAR RAGRLDVAVA HLERLVERAR RDAQPALFLP
MTLVELGYAA EQGGDPATGL ARHAEAFDAA RAMGAPRDAI GALEGIASAA AH
//
