ID   W2EPY4_9ACTN            Unreviewed;       236 AA.
AC   W2EPY4;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 46.
DE   SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:ETK33021.1};
GN   ORFNames=MPTA5024_26745 {ECO:0000313|EMBL:ETK33021.1};
OS   Microbispora sp. ATCC PTA-5024.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Microbispora.
OX   NCBI_TaxID=316330 {ECO:0000313|EMBL:ETK33021.1, ECO:0000313|Proteomes:UP000018869};
RN   [1] {ECO:0000313|EMBL:ETK33021.1, ECO:0000313|Proteomes:UP000018869}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC PTA-5024 {ECO:0000313|EMBL:ETK33021.1,
RC   ECO:0000313|Proteomes:UP000018869};
RX   PubMed=24459268;
RA   Sosio M., Gallo G., Pozzi R., Serina S., Monciardini P., Bera A.,
RA   Stegmann E., Weber T.;
RT   "Draft Genome Sequence of the Microbispora sp. Strain ATCC-PTA-5024,
RT   Producing the Lantibiotic NAI-107.";
RL   Genome Announc. 2:e01198-13(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETK33021.1}.
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DR   EMBL; AWEV01000206; ETK33021.1; -; Genomic_DNA.
DR   RefSeq; WP_036328779.1; NZ_KI866524.1.
DR   AlphaFoldDB; W2EPY4; -.
DR   STRING; 316330.MPTA5024_26745; -.
DR   PATRIC; fig|316330.3.peg.5158; -.
DR   HOGENOM; CLU_000445_30_4_11; -.
DR   OrthoDB; 8927943at2; -.
DR   Proteomes; UP000018869; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00383; trans_reg_C; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR049170; GlnR_N.
DR   InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR039420; WalR-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR48111; REGULATOR OF RPOS; 1.
DR   PANTHER; PTHR48111:SF16; TRANSCRIPTIONAL REGULATORY PROTEIN GLNR; 1.
DR   Pfam; PF21695; GlnR_1st; 1.
DR   Pfam; PF00486; Trans_reg_C; 1.
DR   SMART; SM00862; Trans_reg_C; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   PROSITE; PS51755; OMPR_PHOB; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000018869}.
FT   DOMAIN          125..222
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51755"
FT   DNA_BIND        125..222
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ   SEQUENCE   236 AA;  25690 MW;  CDF0B881ECF2F78E CRC64;
     MSNLLLLTNA LEPSAEVLPA LGLLLHSVRV APAEASALID AAPADAILVD ARRELVQAKS
     LCRLLRTTGV TCPLVAIVTE GGLAAMTAEW GVDDVVLDTA GPAEVEARLR MASGRLSLAA
     AEEVPDEIRS GDLSIDEATY TARLRGRALD LTFKEFELLK YLAQHPGRVF TRAQLLQEVW
     GYDYFGGTRT VDVHVRRLRA KLGAEYEALI GTVRNVGYRF VPDRGEQQNE AEPARR
//