ID W2ESJ6_9ACTN Unreviewed; 438 AA.
AC W2ESJ6;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 13-SEP-2023, entry version 31.
DE RecName: Full=Ammonium transporter {ECO:0000256|RuleBase:RU362002};
GN ORFNames=MPTA5024_21950 {ECO:0000313|EMBL:ETK33941.1};
OS Microbispora sp. ATCC PTA-5024.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Microbispora.
OX NCBI_TaxID=316330 {ECO:0000313|EMBL:ETK33941.1, ECO:0000313|Proteomes:UP000018869};
RN [1] {ECO:0000313|EMBL:ETK33941.1, ECO:0000313|Proteomes:UP000018869}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC PTA-5024 {ECO:0000313|EMBL:ETK33941.1,
RC ECO:0000313|Proteomes:UP000018869};
RX PubMed=24459268;
RA Sosio M., Gallo G., Pozzi R., Serina S., Monciardini P., Bera A.,
RA Stegmann E., Weber T.;
RT "Draft Genome Sequence of the Microbispora sp. Strain ATCC-PTA-5024,
RT Producing the Lantibiotic NAI-107.";
RL Genome Announc. 2:e01198-13(2014).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362002};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362002}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ammonia transporter channel (TC 1.A.11.2)
CC family. {ECO:0000256|ARBA:ARBA00005887, ECO:0000256|RuleBase:RU362002}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETK33941.1}.
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DR EMBL; AWEV01000163; ETK33941.1; -; Genomic_DNA.
DR RefSeq; WP_036327232.1; NZ_KI866524.1.
DR AlphaFoldDB; W2ESJ6; -.
DR STRING; 316330.MPTA5024_21950; -.
DR PATRIC; fig|316330.3.peg.4234; -.
DR HOGENOM; CLU_000445_33_0_11; -.
DR OrthoDB; 9814202at2; -.
DR Proteomes; UP000018869; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR InterPro; IPR029020; Ammonium/urea_transptr.
DR InterPro; IPR001905; Ammonium_transpt.
DR InterPro; IPR018047; Ammonium_transpt_CS.
DR InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR NCBIfam; TIGR00836; amt; 1.
DR PANTHER; PTHR43029; AMMONIUM TRANSPORTER MEP2; 1.
DR PANTHER; PTHR43029:SF10; AMMONIUM TRANSPORTER MEP2; 1.
DR Pfam; PF00909; Ammonium_transp; 1.
DR SUPFAM; SSF111352; Ammonium transporter; 1.
DR PROSITE; PS01219; AMMONIUM_TRANSP; 1.
PE 3: Inferred from homology;
KW Ammonia transport {ECO:0000256|ARBA:ARBA00023177,
KW ECO:0000256|RuleBase:RU362002};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362002};
KW Reference proteome {ECO:0000313|Proteomes:UP000018869};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362002};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362002};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362002}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 38..59
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 105..127
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 134..156
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 168..190
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 202..222
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 234..255
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 264..282
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 288..308
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 320..341
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 361..382
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT DOMAIN 9..412
FT /note="Ammonium transporter AmtB-like"
FT /evidence="ECO:0000259|Pfam:PF00909"
SQ SEQUENCE 438 AA; 45347 MW; 0D798D8A31C6EA95 CRC64;
MKIDTGTTAW MITATALVLL MTPGLAFFYG GMTRAKSVLN MMMMSFVSII TVTIAWVLYG
HTIAFTTFGD ADSFTNKLIG GFDAVGLQSL VDTATKDDGT GMPSLVFSAF QLTFAIITVA
LISGAIADRA KFGAWVVFSV VWATLVYFPV AHWVWGGGWL AGLGIEDFAG GTVVHVNAGA
AGLALALVLG KRSGWRKDPM RPHNLTLVLL GVGLLWFGWF GFNAGSELAV DGTAGLAFMN
TQVATAAAAG AWILVEKLRD GHSTTLGVAS GAVAGLVAIT PACGFVDPWA AVVLGALAGA
VCAYAVGLKY RLGFDDSLDV VGVHLVGGAI GAVSLGIIAR YPFADGQNKG LLYAGPISQL
GVQILGPVAV GLYSFVMAYV IGKIIDKTIG FRVTQEDEVT GIDITTHAET GYDLGTIHSS
GVASVNGPVP AEAKKVDA
//
