ID W2EZS1_9ACTN Unreviewed; 351 AA.
AC W2EZS1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Threonine dehydrogenase {ECO:0000313|EMBL:ETK37125.1};
GN ORFNames=MPTA5024_05585 {ECO:0000313|EMBL:ETK37125.1};
OS Microbispora sp. ATCC PTA-5024.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Microbispora.
OX NCBI_TaxID=316330 {ECO:0000313|EMBL:ETK37125.1, ECO:0000313|Proteomes:UP000018869};
RN [1] {ECO:0000313|EMBL:ETK37125.1, ECO:0000313|Proteomes:UP000018869}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC PTA-5024 {ECO:0000313|EMBL:ETK37125.1,
RC ECO:0000313|Proteomes:UP000018869};
RX PubMed=24459268;
RA Sosio M., Gallo G., Pozzi R., Serina S., Monciardini P., Bera A.,
RA Stegmann E., Weber T.;
RT "Draft Genome Sequence of the Microbispora sp. Strain ATCC-PTA-5024,
RT Producing the Lantibiotic NAI-107.";
RL Genome Announc. 2:e01198-13(2014).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETK37125.1}.
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DR EMBL; AWEV01000054; ETK37125.1; -; Genomic_DNA.
DR RefSeq; WP_036320398.1; NZ_KI866522.1.
DR AlphaFoldDB; W2EZS1; -.
DR STRING; 316330.MPTA5024_05585; -.
DR PATRIC; fig|316330.3.peg.1083; -.
DR HOGENOM; CLU_026673_1_0_11; -.
DR OrthoDB; 9797931at2; -.
DR Proteomes; UP000018869; Unassembled WGS sequence.
DR CDD; cd08230; glucose_DH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR031640; Glu_dehyd_C.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43189:SF2; GLUCOSE 1-DEHYDROGENASE; 1.
DR PANTHER; PTHR43189; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C1198.01-RELATED; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF16912; Glu_dehyd_C; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000018869}.
FT DOMAIN 26..137
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 144..348
FT /note="Glucose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16912"
SQ SEQUENCE 351 AA; 36590 MW; 845323CC7CB2546E CRC64;
MRALTVVPRT GGSLAVSDVP EPEPGPGDLL VDGLAVGVCG TDKEIAAGDY GWAPPGRERL
VIGHESLGRV RRAPSGSGFS PGDLVVGLVR RPDPVPCGAC AHGQFDMCRN GRYTERGIKE
LDGYASESWA VEPEYAVRLD PGLAEVGMLM EPTSVVAKAW EQVDKVGARA WFEPRTALVT
GAGPIGLLAA LLGVQRGLDV HVLDRVTTGP KPGLVAGLGA TYHSGAFDEA VAKARPDVVI
EATGVADVVF DAIATTAPYG IVCLTGVSPA GRRLTVDAGT LNREMVLEND VVVGSVNANM
GHYATAAAAL AEADPAWLMR LISRRVPLDR FAEAFGHEED DVKVVVTLAG S
//
