ID   W2F1C1_9ACTN            Unreviewed;       376 AA.
AC   W2F1C1;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=ROK family transcriptional regulator {ECO:0000313|EMBL:ETK36872.1};
GN   ORFNames=MPTA5024_06675 {ECO:0000313|EMBL:ETK36872.1};
OS   Microbispora sp. ATCC PTA-5024.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Microbispora.
OX   NCBI_TaxID=316330 {ECO:0000313|EMBL:ETK36872.1, ECO:0000313|Proteomes:UP000018869};
RN   [1] {ECO:0000313|EMBL:ETK36872.1, ECO:0000313|Proteomes:UP000018869}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC PTA-5024 {ECO:0000313|EMBL:ETK36872.1,
RC   ECO:0000313|Proteomes:UP000018869};
RX   PubMed=24459268;
RA   Sosio M., Gallo G., Pozzi R., Serina S., Monciardini P., Bera A.,
RA   Stegmann E., Weber T.;
RT   "Draft Genome Sequence of the Microbispora sp. Strain ATCC-PTA-5024,
RT   Producing the Lantibiotic NAI-107.";
RL   Genome Announc. 2:e01198-13(2014).
CC   -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC       {ECO:0000256|ARBA:ARBA00006479}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETK36872.1}.
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DR   EMBL; AWEV01000063; ETK36872.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2F1C1; -.
DR   STRING; 316330.MPTA5024_06675; -.
DR   PATRIC; fig|316330.3.peg.1292; -.
DR   HOGENOM; CLU_036604_13_0_11; -.
DR   Proteomes; UP000018869; Unassembled WGS sequence.
DR   Gene3D; 3.30.420.40; -; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000600; ROK.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR   PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR   Pfam; PF00480; ROK; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01125; ROK; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018869}.
FT   REGION          348..376
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   376 AA;  39339 MW;  6B09878C540D0F27 CRC64;
     MDYLRDYNDA SVVAVARRAG VFDRAMIASA TGLTPQAVSK VVARLVAAGL VEPDGVRRHG
     VGKPASVYRL VPDSRYAIGA HVARGTLRMV LSDLTGRVLQ TVARPLPPDF TPGRLLDELS
     AGVGALAGEC RAGRLVGVGI GMVGPLDHAQ GVVRDAHRLR HWHDVPLREM AAERLGLPVL
     LDKDVAAGVV GEAWLGGVDV RDAALIMVES GIGAGLWLGG GVYRGAHTNA GEFGHMVVQV
     DGPECVCGRR GCLEILHDRA LAAGEAGTAA RVLAVGVVNL LQTLDVDHVV LAGADLLPHA
     ATYLDVVRTA VRTEVPRADW LAVEVTTSRL GTDVIAAGAA MEMLNERYGL PREPRPGERV
     PGPGAARPGG RPPSRA
//