ID W2F204_9ACTN Unreviewed; 340 AA.
AC W2F204;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=HTH lacI-type domain-containing protein {ECO:0000259|PROSITE:PS50932};
GN ORFNames=MPTA5024_01160 {ECO:0000313|EMBL:ETK37984.1};
OS Microbispora sp. ATCC PTA-5024.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Microbispora.
OX NCBI_TaxID=316330 {ECO:0000313|EMBL:ETK37984.1, ECO:0000313|Proteomes:UP000018869};
RN [1] {ECO:0000313|EMBL:ETK37984.1, ECO:0000313|Proteomes:UP000018869}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC PTA-5024 {ECO:0000313|EMBL:ETK37984.1,
RC ECO:0000313|Proteomes:UP000018869};
RX PubMed=24459268;
RA Sosio M., Gallo G., Pozzi R., Serina S., Monciardini P., Bera A.,
RA Stegmann E., Weber T.;
RT "Draft Genome Sequence of the Microbispora sp. Strain ATCC-PTA-5024,
RT Producing the Lantibiotic NAI-107.";
RL Genome Announc. 2:e01198-13(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETK37984.1}.
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DR EMBL; AWEV01000015; ETK37984.1; -; Genomic_DNA.
DR RefSeq; WP_036318818.1; NZ_KI866522.1.
DR AlphaFoldDB; W2F204; -.
DR STRING; 316330.MPTA5024_01160; -.
DR PATRIC; fig|316330.3.peg.220; -.
DR HOGENOM; CLU_037628_6_1_11; -.
DR OrthoDB; 3227375at2; -.
DR Proteomes; UP000018869; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000018869};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 8..53
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 340 AA; 36509 MW; E4AF02D66C97DCBE CRC64;
MGRMTGRSTL KEVAERAGVS IGTASAVFAG KPWVSSATGS VVRRAAEELG YRPRGRKPAE
TGMIGFVSWV SELFSPDNLY YAPVLYGAQQ ACAELDLSMT YEVIQPQEDR LPLCVERGQV
AGLLVLNVGV SRDYLARILD AGVSCVLLEH AVLDLPVDYV RHDDETGGYL ATRHLIGLGH
TAPPPAIITA GEHIVPASRR LAGYRRALAE HGLAAGPAYV RRGDFSARTG YEQMAALLDL
PVPPTAVFCA NDVSAIGALD ALRERGLRVP GDVSVIGYDD VAMAAHASPP LTTIASDKEL
LGAQAVWHLV QRVRRPETTS RDTVLGVRLV ERRSTAPPRR
//
