ID W2G2S6_PHYPR Unreviewed; 1019 AA.
AC W2G2S6;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=cellulose synthase (UDP-forming) {ECO:0000256|ARBA:ARBA00012539};
DE EC=2.4.1.12 {ECO:0000256|ARBA:ARBA00012539};
GN ORFNames=L915_16421 {ECO:0000313|EMBL:ETK77307.1}, L917_16129
GN {ECO:0000313|EMBL:ETL83996.1};
OS Phytophthora parasitica (Potato buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4792 {ECO:0000313|EMBL:ETK77307.1};
RN [1] {ECO:0000313|EMBL:ETL83996.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHvinca01 {ECO:0000313|EMBL:ETL83996.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETK77307.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CJ02B3 {ECO:0000313|EMBL:ETK77307.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CJ02B3.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KI688443; ETK77307.1; -; Genomic_DNA.
DR EMBL; KI681921; ETL83996.1; -; Genomic_DNA.
DR SMR; W2G2S6; -.
DR EnsemblProtists; ETK77307; ETK77307; L915_16421.
DR EnsemblProtists; ETL83996; ETL83996; L917_16129.
DR VEuPathDB; FungiDB:PPTG_16268; -.
DR OMA; KWEPGAT; -.
DR Proteomes; UP000053236; Unassembled WGS sequence.
DR Proteomes; UP000054423; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00821; PH; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR43867; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR PANTHER; PTHR43867:SF2; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR Pfam; PF13632; Glyco_trans_2_3; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Cellulose biosynthesis {ECO:0000256|ARBA:ARBA00022916};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 208..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 801..829
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 876..895
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 916..938
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 950..970
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 991..1010
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 68..180
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
SQ SEQUENCE 1019 AA; 115541 MW; 51C5482EF31DD407 CRC64;
MANRQPPGLG ALPEDAQYSQ TPLSGAQYHE QLSSAAAPGK KLLSQATMDV QNTINELTKA
KEHEELGKIT VHGWMHKQGS RKFKGPVAKS WRKRYFALEG AKMYYFHSDV DCRKYFNSRN
GELVVGAIDL RDAFKLEQSE RLDLPARGIV IHTRHRAWLV CPETDQDFTM WFDALEFTVM
SAGSGNVVKR DLPNVRVYEM KGRFSYRFWY VIFVITALIE LAGIVLWFPL GIEPCDVKYK
TDTCEEIQLL YADTLQCGDK PFNGVWDPPQ WYHWSAGIET VQCFKEPHIG DWVSYFLFYL
AEFISISLGF LYYLGMWKPV RRGARYLRDF EPHFPPEKWP TVDILLCHYA EPAEDTIATL
EKIMNLDYPP HLFHVWICDD GYCKSKWEAG AAVPKVSVNT GVIEDAGDVR HEVAQFMYDR
VCESYELEVD EWRKEHTTVK MPTNANPRIV NRADCAVGSV RDDYHYHGLP KLTFVGRIKP
PVHHSKAGNI NNVLYNEGAC GRYAIILDND MKPHEMFIQA TLPFFFDVPQ NSKITRCCAP
GCGDIGKICC ALCQAAGVPE AQIMYCSKDC YNASGHVKSS VHRRQTQNTM SERMMCASCG
SKINQKKGLC RKCNRAVSQR DSNQFVGVSA DDYSDHVSVN QVGYVQTPQY FEDCLQLRLG
DPCGHRNSTF FDSAQTGMDG YDCASFAGTN AIFRREALDS VCGIQYGSLT EDAYTGKMMV
DKGWKGYYFR KDLEGEEADR IRLAEGAVPE SVAAALAQRK RWAKGNFQIF LRNKKSLVDP
EWVPPQVELP PKRKINKFMR WVFFMNLTVY PIGSFPAIFF FYITGYFLYT GQAPIYTSGL
RLLMALVPKI VAQSILSALS NRTVDNDDVL RSQQTWFSYA FVHVMAVFET IYWKITGKEA
AWANTGALGG NSIMELPNLL VFLAMVFGMM WDTVRYFAGY NNAATTHGTP LYFASLFLGG
FLASQLGPMV RMSLQTYFGW SHKSLTDQGN IVGSFSLAFV LIILCIWVYV ETPNHSIFG
//
